On the Move-Sensitive Fluorescent Aptassay on Board Catalytic Micromotors for the Determination of Interleukin-6 in Ultra-Low Serum Volumes for Neonatal Sepsis Diagnostics.
fluorescence microscopy
graphene
interleukin-6
micromotors
neonate sepsis
on-the-move aptassay
Journal
ACS sensors
ISSN: 2379-3694
Titre abrégé: ACS Sens
Pays: United States
ID NLM: 101669031
Informations de publication
Date de publication:
28 10 2022
28 10 2022
Historique:
pubmed:
6
10
2022
medline:
1
11
2022
entrez:
5
10
2022
Statut:
ppublish
Résumé
A graphene oxide/nickel/platinum nanoparticle micromotor (MM)-based fluorescent aptassay is proposed to determine interleukin-6 (IL-6) in serum samples from low-birth-weight infants (gestational age of less than 32 weeks and birthweight below 1000 g) with sepsis suspicion. In this kind of patients, IL-6 has demonstrated good sensitivity and specificity for the diagnosis of sepsis, both for early and late onset sepsis. The approach was based on the adsorption of the aptamer for IL-6 tagged with 6-FAM as a fluorescent label (Apt
Identifiants
pubmed: 36198198
doi: 10.1021/acssensors.2c01635
pmc: PMC9623581
doi:
Substances chimiques
Interleukin-6
0
graphene oxide
0
APT
7320-57-2
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
3144-3152Commentaires et corrections
Type : ErratumIn
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