Autonomic nervous system and arrhythmias in structural heart disease.
Atrial fibrillation
Autonomic nervous system
Neuromodulation
Ventricular tachycardia
Journal
Autonomic neuroscience : basic & clinical
ISSN: 1872-7484
Titre abrégé: Auton Neurosci
Pays: Netherlands
ID NLM: 100909359
Informations de publication
Date de publication:
12 2022
12 2022
Historique:
received:
22
07
2021
revised:
21
09
2022
accepted:
21
09
2022
pubmed:
7
10
2022
medline:
18
11
2022
entrez:
6
10
2022
Statut:
ppublish
Résumé
The autonomic nervous system functions in a fine-tuned manner to dynamically modulate cardiac function during normal physiological state. Autonomic dysregulation in cardiac disease states such as myocardial infarction and heart failure alters this fine balance, which in turn promotes disease progression and arrhythmogenesis. Neuromodulatory interventions that aim to restore this balance at distinct levels of the cardiac neuraxis thus have been shown to be effective in the treatment of arrhythmias. This review first describes the anatomy of the cardiac autonomic nervous system and the pathological changes that occur with neural remodeling in the setting of scar and cardiomyopathy, followed by therapeutic interventions for neuraxial modulation of arrhythmias such as atrial fibrillation and ventricular tachyarrhythmias.
Identifiants
pubmed: 36201902
pii: S1566-0702(22)00096-0
doi: 10.1016/j.autneu.2022.103037
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
103037Informations de copyright
Copyright © 2022. Published by Elsevier B.V.