A contiguous de novo genome assembly of sugar beet EL10 (Beta vulgaris L.).


Journal

DNA research : an international journal for rapid publication of reports on genes and genomes
ISSN: 1756-1663
Titre abrégé: DNA Res
Pays: England
ID NLM: 9423827

Informations de publication

Date de publication:
01 Feb 2023
Historique:
received: 11 04 2022
revised: 26 08 2022
accepted: 12 09 2022
pubmed: 9 10 2022
medline: 7 2 2023
entrez: 8 10 2022
Statut: ppublish

Résumé

A contiguous assembly of the inbred 'EL10' sugar beet (Beta vulgaris ssp. vulgaris) genome was constructed using PacBio long-read sequencing, BioNano optical mapping, Hi-C scaffolding, and Illumina short-read error correction. The EL10.1 assembly was 540 Mb, of which 96.2% was contained in nine chromosome-sized pseudomolecules with lengths from 52 to 65 Mb, and 31 contigs with a median size of 282 kb that remained unassembled. Gene annotation incorporating RNA-seq data and curated sequences via the MAKER annotation pipeline generated 24,255 gene models. Results indicated that the EL10.1 genome assembly is a contiguous genome assembly highly congruent with the published sugar beet reference genome. Gross duplicate gene analyses of EL10.1 revealed little large-scale intra-genome duplication. Reduced gene copy number for well-annotated gene families relative to other core eudicots was observed, especially for transcription factors. Variation in genome size in B. vulgaris was investigated by flow cytometry among 50 individuals producing estimates from 633 to 875 Mb/1C. Read-depth mapping with short-read whole-genome sequences from other sugar beet germplasm suggested that relatively few regions of the sugar beet genome appeared associated with high-copy number variation.

Identifiants

pubmed: 36208288
pii: 6748264
doi: 10.1093/dnares/dsac033
pmc: PMC9896481
pii:
doi:

Substances chimiques

Sugars 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : USDA-ARS CRIS
ID : 3635-21000-011-00D
Organisme : Beet Sugar Development Foundation
Organisme : Intramural Research Program of the National Human Genome Research Institute
Organisme : National Institutes of Health

Informations de copyright

Published by Oxford University Press for the Infectious Diseases Society of America 2022.

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Auteurs

J Mitchell McGrath (JM)

USDA-ARS Sugarbeet and Bean Research Unit, Michigan State University, 1066 Bogue St., East Lansing, MI 48824, USA.

Andrew Funk (A)

Plant Breeding, Genetics, and Biotechnology Program, Michigan State University, East Lansing, MI 48824, USA.

Paul Galewski (P)

Plant Breeding, Genetics, and Biotechnology Program, Michigan State University, East Lansing, MI 48824, USA.

Shujun Ou (S)

Plant Breeding, Genetics, and Biotechnology Program, Michigan State University, East Lansing, MI 48824, USA.

Belinda Townsend (B)

Department of Plant Sciences, Rothamsted Research, West Common, Harpenden, Hertfordshire AL5 2JQ, UK.

Karen Davenport (K)

Los Alamos Nat'l Lab, Biosecurity and Public Health, Los Alamos, NM 87545, USA.

Hajnalka Daligault (H)

Los Alamos Nat'l Lab, Biosecurity and Public Health, Los Alamos, NM 87545, USA.

Shannon Johnson (S)

Los Alamos Nat'l Lab, Biosecurity and Public Health, Los Alamos, NM 87545, USA.

Joyce Lee (J)

BioNano Genomics, 9640 Towne Centre Drive, San Diego, CA 92121, USA.

Alex Hastie (A)

BioNano Genomics, 9640 Towne Centre Drive, San Diego, CA 92121, USA.

Aude Darracq (A)

SESVANDERHAVE N.V., Industriepark Soldatenplein Zone 2 Nr 15, 3300 Tienen, Belgium.

Glenda Willems (G)

SESVANDERHAVE N.V., Industriepark Soldatenplein Zone 2 Nr 15, 3300 Tienen, Belgium.

Steve Barnes (S)

SESVANDERHAVE N.V., Industriepark Soldatenplein Zone 2 Nr 15, 3300 Tienen, Belgium.

Ivan Liachko (I)

Phase Genomics, 4000 Mason Road, Suite 225, Seattle, WA 98195, USA.

Shawn Sullivan (S)

Phase Genomics, 4000 Mason Road, Suite 225, Seattle, WA 98195, USA.

Sergey Koren (S)

Genome Informatics Section, Computational and Statistical Genomics Branch, National Human Genome Research Institute, Bethesda, MD, USA.

Adam Phillippy (A)

Genome Informatics Section, Computational and Statistical Genomics Branch, National Human Genome Research Institute, Bethesda, MD, USA.

Jie Wang (J)

Center for Genomics-Enabled Plant Science, Plant Biology Department, Michigan State University, East Lansing, MI 48824, USA.

Tiffany Liu (T)

Center for Genomics-Enabled Plant Science, Plant Biology Department, Michigan State University, East Lansing, MI 48824, USA.

Jane Pulman (J)

Center for Genomics-Enabled Plant Science, Plant Biology Department, Michigan State University, East Lansing, MI 48824, USA.

Kevin Childs (K)

Center for Genomics-Enabled Plant Science, Plant Biology Department, Michigan State University, East Lansing, MI 48824, USA.

Shengqiang Shu (S)

United States Department of Energy, Joint Genome Institute, Berkeley, CA, USA.

Anastasia Yocum (A)

A2IDEA, 674 S. Wagner Rd., Ann Arbor, MI 48103, USA.

Damian Fermin (D)

A2IDEA, 674 S. Wagner Rd., Ann Arbor, MI 48103, USA.

Effie Mutasa-Göttgens (E)

University of Hertfordshire, Division of Biosciences, Hatfield, Hertfordshire AL10 9AB, UK.

Piergiorgio Stevanato (P)

DAFNAE, University of Padova, Viale Università 16, 35020 Legnaro (PD), Italy.

Kazunori Taguchi (K)

Hokkaido Agricultural Research Center, National Agriculture and Food Research Organization, Shinsei Memuro, Hokkaido 082-0081, Japan.

Rachel Naegele (R)

USDA-ARS Sugarbeet and Bean Research Unit, Michigan State University, 1066 Bogue St., East Lansing, MI 48824, USA.

Kevin M Dorn (KM)

USDA-ARS Soil Management and Sugarbeet Research Unit, Crops Research Laboratory, 1701 Centre Ave, Fort Collins, CO 80526, USA.

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