Specific disruption of the ventral anterior temporo-frontal network reveals key implications for language comprehension and cognition.
Journal
Communications biology
ISSN: 2399-3642
Titre abrégé: Commun Biol
Pays: England
ID NLM: 101719179
Informations de publication
Date de publication:
10 10 2022
10 10 2022
Historique:
received:
19
07
2020
accepted:
12
09
2022
entrez:
10
10
2022
pubmed:
11
10
2022
medline:
13
10
2022
Statut:
epublish
Résumé
Recent investigations have raised the question of the role of the anterior lateral temporal cortex in language processing (ventral language network). Here we present the language and overall cognitive performance of a rare male patient with chronic middle cerebral artery cerebrovascular accident with a well-documented lesion restricted to the anterior temporal cortex and its connections via the extreme capsule with the pars triangularis of the inferior frontal gyrus (i.e. Broca's region). The performance of this unique patient is compared with that of two chronic middle cerebral artery cerebrovascular accident male patients with damage to the classic dorsal posterior temporo-parietal language system. Diffusion tensor imaging is used to reconstruct the relevant white matter tracts of the three patients, which are also compared with those of 10 healthy individuals. The patient with the anterior temporo-frontal lesion presents with flawless and fluent speech, but selective impairment in accessing lexico-semantic information, in sharp contrast to the impairments in speech, sentence comprehension and repetition observed after lesions to the classic dorsal language system. The present results underline the contribution of the ventral language stream in lexico-semantic processing and higher cognitive functions, such as active selective controlled retrieval.
Identifiants
pubmed: 36217017
doi: 10.1038/s42003-022-03983-9
pii: 10.1038/s42003-022-03983-9
pmc: PMC9551096
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1077Informations de copyright
© 2022. The Author(s).
Références
Neuroimage. 2006 May 1;30(4):1414-32
pubmed: 16413796
Sci Am. 1967 Aug;217(2):24-9
pubmed: 4962491
Cereb Cortex. 2007 Dec;17(12):2769-76
pubmed: 17339607
Brain. 2009 Dec;132(Pt 12):3411-27
pubmed: 19942676
Front Neuroanat. 2016 May 24;10:58
pubmed: 27252628
Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):1919-24
pubmed: 26831102
Neuropsychology. 2006 Sep;20(5):529-38
pubmed: 16938015
Curr Opin Neurobiol. 2013 Apr;23(2):250-4
pubmed: 23146876
Trends Neurosci. 2003 Feb;26(2):100-7
pubmed: 12536133
Brain Struct Funct. 2020 Jan;225(1):85-119
pubmed: 31773331
PLoS Biol. 2009 Aug;7(8):e1000170
pubmed: 19668354
Brain. 1992 Dec;115 ( Pt 6):1783-806
pubmed: 1486461
Cortex. 2011 May;47(5):575-87
pubmed: 20074721
Eur J Neurosci. 2003 Apr;17(7):1489-97
pubmed: 12713652
Brain. 2010 Nov;133(11):3243-55
pubmed: 20952378
Sci Am. 1998 Jul;279(1):50-5
pubmed: 9648298
Q J Exp Psychol (Hove). 2009 Jul;62(7):1420-9
pubmed: 19048451
Brain Lang. 2014 Apr;131:36-55
pubmed: 24182840
J Clin Exp Neuropsychol. 2009 Oct;31(7):803-8
pubmed: 19142771
J Neurosci. 2011 Nov 23;31(47):16949-57
pubmed: 22114265
Front Hum Neurosci. 2021 Jun 22;15:635750
pubmed: 34239424
Brain. 2011 Oct;134(Pt 10):3094-105
pubmed: 21685458
Neuroimage. 2012 Jul 16;61(4):957-65
pubmed: 22440645
Neurosci Biobehav Rev. 2018 Sep;92:104-127
pubmed: 29753752
Sci Rep. 2020 May 18;10(1):8186
pubmed: 32424290
Nat Rev Neurosci. 2007 Dec;8(12):976-87
pubmed: 18026167
J Int Neuropsychol Soc. 2004 Mar;10(2):164-72
pubmed: 15012836
Neurology. 2011 Mar 15;76(11):1006-14
pubmed: 21325651
Behav Neurol. 2010;22(3-4):111-9
pubmed: 20595743
Clin Neurosurg. 1969;16:269-87
pubmed: 5811709
J Neuroradiol. 2019 Feb;46(1):52-60
pubmed: 30098370
Science. 1970 Nov 27;170(3961):940-4
pubmed: 5475022
Cortex. 2014 Jul;56:73-84
pubmed: 23137651
J Neuropsychol. 2016 Sep;10(2):317-43
pubmed: 25708527
Med Phys. 2011 Jul;38(7):4415-21
pubmed: 21859042
Neuroimage. 2018 Jan 15;165:102-111
pubmed: 29024793
Front Hum Neurosci. 2017 May 04;11:225
pubmed: 28522967
Sci Rep. 2018 Sep 25;8(1):14352
pubmed: 30254222
Cognition. 2004 May-Jun;92(1-2):67-99
pubmed: 15037127
Nat Neurosci. 2011 Sep 18;14(10):1245-6
pubmed: 21926985
Brain. 1980 Jun;103(2):337-50
pubmed: 7397481
J Neurosci. 2008 Nov 5;28(45):11435-44
pubmed: 18987180
Brain. 2009 Dec;132(Pt 12):3401-10
pubmed: 19892765
Eur J Neurosci. 2010 Aug;32(3):383-98
pubmed: 20662902
Proc Natl Acad Sci U S A. 2008 Nov 18;105(46):18035-40
pubmed: 19004769
Annu Rev Neurosci. 2002;25:151-88
pubmed: 12052907
Brain. 2015 Aug;138(Pt 8):2423-37
pubmed: 26112340
J Neurol Neurosurg Psychiatry. 1996 Aug;61(2):176-80
pubmed: 8708686
Brain. 2013 Feb;136(Pt 2):619-29
pubmed: 23378217
Behav Neurol. 2000;12(4):191-200
pubmed: 11568431
Neurology. 2013 Jul 30;81(5):456-62
pubmed: 23897873
Neuroimage. 2007 Jul 1;36(3):630-44
pubmed: 17481925
Proc Natl Acad Sci U S A. 1995 Jun 20;92(13):5803-7
pubmed: 7597032
Brain Struct Funct. 2022 Mar;227(2):529-544
pubmed: 34731328
Clin Neuropsychol. 2008 Sep;22(5):842-50
pubmed: 17934999
IEEE Trans Med Imaging. 2004 Jul;23(7):789-98
pubmed: 15250631