Transcatheter aortic valve replacement with or without anesthesiologist: results from a high-volume single center.


Journal

Journal of cardiovascular medicine (Hagerstown, Md.)
ISSN: 1558-2035
Titre abrégé: J Cardiovasc Med (Hagerstown)
Pays: United States
ID NLM: 101259752

Informations de publication

Date de publication:
01 12 2022
Historique:
pubmed: 12 10 2022
medline: 11 11 2022
entrez: 11 10 2022
Statut: ppublish

Résumé

Local instead of general anesthesia has become the standard approach in many centers for transfemoral transcatheter aortic valve replacement (TAVR). New generation devices and an increase in operator skills had led to a drastic reduction in periprocedural complications, bringing in the adoption of a minimalist approach. In our study, we aimed to compare patients treated with TAVR under local anesthesia with or without the presence of an anesthesiologist on site (AOS). We compare procedural aspects and results of patients treated with TAVR with an AOS against patients treated with TAVR with an anesthesiologist on call (AOC). From January 2019 to December 2020, all consecutive patients undergoing transfemoral TAVR with either the self-expandable Evolut (Medtronic, MN, USA) or balloon-expandable SAPIEN 3 (Edwards Lifesciences, CA, USA) were collected. Of 332 patients collected, 96 (29%) were treated with TAVR with AOS, while 236 (71%) were treated with TAVR with AOC. No differences in procedural time, fluoroscopy time and amount of contrast medium were observed. No procedural death and conversion to open-chest surgery was reported. The rate of stroke/transient ischemic attacks and major vascular complications was similar in the two groups. No patients in both groups required conversion to general anesthesia. Two patients (0.8%) in the AOC group required urgent intervention of the anesthesiologist. In the AOC group, there was a greater use of morphine (55.9% vs. 33.3%, P  = 0.008), but with a lower dose for each patient (2.0 vs. 2.8 mg, P  = 0.006). On the other hand, there was a lower use of other painkiller drugs (3.4% vs. 20.8%, P  = 0.001). No difference in inotropic drugs use was observed. In patients at low or intermediate risk undergoing transfemoral TAVR, a safe procedure can be performed under local anesthesia without the presence of an anesthesiologist in the catheterization laboratory.

Identifiants

pubmed: 36219144
doi: 10.2459/JCM.0000000000001391
pii: 01244665-202212000-00008
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

801-806

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2022 Italian Federation of Cardiology - I.F.C. All rights reserved.

Références

Vahanian A, Beyersdorf F, Praz F, Milojevic M, Baldus S, Bauersachs J, et al. 2021 ESC/EACTS Guidelines for the management of valvular heart disease. Eur Heart J 2022; 43:561–632.
Wood DA, Lauck SB, Cairns JA, Humphries KH, Cook R, Welsh R, et al. The Vancouver 3 M (Multidisciplinary, Multimodality, But Minimalist) clinical pathway facilitates safe next-day discharge home at low-, medium- and high-volume transfemoral transcatheter aortic valve replacement centers: the 3M TAVR Study. JACC Cardiovasc Interv 2019; 12:459–469.
Thiele H, Kurz T, Feistritzer HJ, Stachel G, Hartung P, Lurz P, et al. General versus local anesthesia with conscious sedation in transcatheter aortic valve implantation: the randomized SOLVE-TAVI Trial. Circulation 2020; 142:1437–1447.
Harjai KJ, Bules T, Berger A, Young B, Singh D, Carter R, et al. Efficiency, safety, and quality of life after transcatheter aortic valve implantation performed with moderate sedation versus general anesthesia. Am J Cardiol 2020; 125:1088–1095.
Petronio AS, Giannini C, De Carlo M, Bedogni F, Colombo A, Tamburino C, et al. Anaesthetic management of transcatheter aortic valve implantation: results from the Italian CoreValve registry. Eurointervention 2016; 12:381–388.
Saia F, Palmierini T, Marcelli C, Chiarabelli M, Taglieri N, Ghetti G, et al. Routine minimalist transcatheter aortic valve implantation with local anesthesia only. J Cardiovasc Med (Hagerstown, Md) 2020; 21:805–811.
Villablanca PA, Mohananey D, Nikolic K, Bangalore S, Slovut DP, Mathew V, et al. Comparison of local versus general anesthesia in patients undergoing transcatheter aortic valve replacement: a meta-analysis. Catheter Cardiovasc Interv 2018; 91:330–342.
Konigstein M, Ben-Shoshan J, Zahler D, Flint N, Granot Y, Aviram G, et al. Outcome of patients undergoing TAVR with and without the attendance of an anesthesiologist. Int J Cardiol 2017; 241:124–127.
Lauck SB, Wood DA, Baumbusch J, Kwon JY, Stub D, Achtem L, et al. Vancouver transcatheter aortic valve replacement clinical pathway: minimalist approach, standardized care, and discharge criteria to reduce length of stay. Circ Cardiovasc Qual Outcomes 2016; 9:312–321.
van der Wulp K, van Wely M, van Heijningen L, van Bakel B, Schoon Y, Verkroost M, et al. Delirium after transcatheter aortic valve implantation under general anesthesia: incidence, predictors, and relation to long-term survival. J Am Geriatr Soc 2019; 67:2325–2330.
Généreux P, Piazza N, Alu MC, Nazif T, Hahn RT, Pibarot P, et al. Valve academic research consortium 3: updated endpoint definitions for aortic valve clinical research. J Am Coll Cardiol 2021; 77:2717–2746.
Junquera L, Urena M, Latib A, Munoz-Garcia A, Nombela-Franco L, Faurie B, et al. Comparison of transfemoral versus transradial secondary access in transcatheter aortic valve replacement. Circ Cardiovasc Interv 2020; 13:
Leon MB, Smith CR, Mack MJ, Makkar RR, Svensson LG, Kodali SK, et al. Transcatheter or surgical aortic-valve replacement in intermediate-risk patients. N Engl J Med 2016; 374:1609–1620.
Mack MJ, Leon MB, Thourani VH, Makkar R, Kodali SK, Russo M, et al. Transcatheter aortic-valve replacement with a balloon-expandable valve in low-risk patients. N Engl J Med 2019; 380:1695–1705.
Reardon MJ, Van Mieghem NM, Popma JJ, Kleiman NS, Sondergaard L, Mumtaz M, et al. Surgical or transcatheter aortic-valve replacement in intermediate-risk patients. N Engl J Med 2017; 376:1321–1331.
Popma JJ, Deeb GM, Yakubov SJ, Mumtaz M, Gada H, O’Hair D, et al. Transcatheter aortic-valve replacement with a self-expanding valve in low-risk patients. N Engl J Med 2019; 380:1706–1715.

Auteurs

Marco Angelillis (M)

Catheterization laboratory, Cardiothoracic and Vascular Department.

Laura Stazzoni (L)

Catheterization laboratory, Cardiothoracic and Vascular Department.

Giulia Costa (G)

Catheterization laboratory, Cardiothoracic and Vascular Department.

Cristina Giannini (C)

Catheterization laboratory, Cardiothoracic and Vascular Department.

Chiara Primerano (C)

Catheterization laboratory, Cardiothoracic and Vascular Department.

Paolo Spontoni (P)

Catheterization laboratory, Cardiothoracic and Vascular Department.

Andrea Pieroni (A)

Catheterization laboratory, Cardiothoracic and Vascular Department.

Fabio Guarracino (F)

Cardiothoracic and vascular Anaesthesiology and Intensive Care, Department of Anesthesia and Critical Care Medicine, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.

Pietro Bertini (P)

Cardiothoracic and vascular Anaesthesiology and Intensive Care, Department of Anesthesia and Critical Care Medicine, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.

Rubia Baldassarri (R)

Cardiothoracic and vascular Anaesthesiology and Intensive Care, Department of Anesthesia and Critical Care Medicine, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.

Marco De Carlo (M)

Catheterization laboratory, Cardiothoracic and Vascular Department.

Anna S Petronio (AS)

Catheterization laboratory, Cardiothoracic and Vascular Department.

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