Maturation and circuit integration of transplanted human cortical organoids.

Animals Animals, Newborn Autistic Disorder Humans Long QT Syndrome Motivation Neural Pathways Neurons / physiology Optogenetics Organoids / cytology Rats Reward Somatosensory Cortex / cytology Stem Cells / cytology Syndactyly

Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
10 2022
Historique:
received: 16 12 2021
accepted: 25 08 2022
entrez: 12 10 2022
pubmed: 13 10 2022
medline: 15 10 2022
Statut: ppublish

Résumé

Self-organizing neural organoids represent a promising in vitro platform with which to model human development and disease

Identifiants

DOI: 10.1038/s41586-022-05277-w PMID: 36224417 PMC: PMC9556304
pubmed: 36224417
doi: 10.1038/s41586-022-05277-w
pii: 10.1038/s41586-022-05277-w
pmc: PMC9556304
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

319-326

Subventions

Organisme : NINDS NIH HHS
ID : K08 NS123544
Pays : United States
Organisme : NIMH NIH HHS
ID : T32 MH019938
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH115012
Pays : United States
Organisme : NIDA NIH HHS
ID : K99 DA050662
Pays : United States

Commentaires et corrections

Type : CommentIn
Type : CommentIn

Informations de copyright

© 2022. The Author(s).

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Auteurs

Omer Revah (O)

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute and Bio-X, Stanford University, Stanford, CA, USA.
ORCID: 0000-0002-4002-5689

Felicity Gore (F)

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Department of Bioengineering, Stanford University, Stanford, CA, USA.

Kevin W Kelley (KW)

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute and Bio-X, Stanford University, Stanford, CA, USA.

Jimena Andersen (J)

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute and Bio-X, Stanford University, Stanford, CA, USA.
ORCID: 0000-0001-9320-6507

Noriaki Sakai (N)

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.

Xiaoyu Chen (X)

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute and Bio-X, Stanford University, Stanford, CA, USA.

Min-Yin Li (MY)

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute and Bio-X, Stanford University, Stanford, CA, USA.
ORCID: 0000-0002-8102-632X

Fikri Birey (F)

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute and Bio-X, Stanford University, Stanford, CA, USA.

Xiao Yang (X)

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute and Bio-X, Stanford University, Stanford, CA, USA.
Department of Chemistry, Stanford University, Stanford, CA, USA.
ORCID: 0000-0003-1504-4949

Nay L Saw (NL)

Stanford Behavioral and Functional Neuroscience Laboratory, Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA, USA.

Samuel W Baker (SW)

Department of Comparative Medicine, Stanford University, Stanford, CA, USA.

Neal D Amin (ND)

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute and Bio-X, Stanford University, Stanford, CA, USA.
ORCID: 0000-0003-2027-1329

Shravanti Kulkarni (S)

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute and Bio-X, Stanford University, Stanford, CA, USA.

Rachana Mudipalli (R)

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Department of Bioengineering, Stanford University, Stanford, CA, USA.
ORCID: 0000-0003-3508-1464

Bianxiao Cui (B)

Department of Chemistry, Stanford University, Stanford, CA, USA.
ORCID: 0000-0002-8044-5629

Seiji Nishino (S)

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.

Gerald A Grant (GA)

Department of Neurosurgery, Stanford University, Stanford, CA, USA.

Juliet K Knowles (JK)

Department of Neurology and Neurological Sciences, Stanford, CA, USA.

Mehrdad Shamloo (M)

Stanford Behavioral and Functional Neuroscience Laboratory, Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA, USA.
Department of Neurosurgery, Stanford University, Stanford, CA, USA.

John R Huguenard (JR)

Department of Neurology and Neurological Sciences, Stanford, CA, USA.

Karl Deisseroth (K)

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Department of Bioengineering, Stanford University, Stanford, CA, USA.
Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA.
ORCID: 0000-0001-9440-3967

Sergiu P Pașca (SP)

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA. spasca@stanford.edu.
Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute and Bio-X, Stanford University, Stanford, CA, USA. spasca@stanford.edu.
ORCID: 0000-0002-3216-3248

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Maturation and circuit integration of...
questionsmedicales.fr › Eucaryotes › Animaux › Groupes animaux › Animaux nouveau-nés › Maturation and circuit integration of...
questionsmedicales.fr › Troubles mentaux › Troubles du développement neurologique › Troubles généralisés du développement de l'enfant › Trouble du spectre autistique › Trouble autistique › Maturation and circuit integration of...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Maturation and circuit integration of...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Troubles du rythme cardiaque › Syndrome du QT long › Maturation and circuit integration of...
questionsmedicales.fr › Comportement et mécanismes comportementaux › Personnalité › Intelligence › Intelligence émotionnelle › Motivation › Maturation and circuit integration of...
questionsmedicales.fr › Système nerveux › Voies nerveuses › Maturation and circuit integration of...
questionsmedicales.fr › Cellules › Neurones › Maturation and circuit integration of...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Optogénétique › Maturation and circuit integration of...
questionsmedicales.fr › Tissus › Organoïdes › Maturation and circuit integration of...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Maturation and circuit integration of...
questionsmedicales.fr › Phénomènes psychologiques › Processus mentaux › Renforcement (psychologie) › Récompense › Maturation and circuit integration of...
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Prosencéphale › Télencéphale › Cerveau › Cortex cérébral › Cortex sensorimoteur › Cortex somatosensoriel › Maturation and circuit integration of...
questionsmedicales.fr › Cellules › Cellules souches › Maturation and circuit integration of...
questionsmedicales.fr › Malformations et maladies congénitales, héréditaires et néonatales › Malformations › Malformations de l'appareil locomoteur › Synostose › Syndactylie › Maturation and circuit integration of...