Nanomaterials: A Review about Halloysite Nanotubes, Properties, and Application in the Biological Field.

biocompatibility biomedical application drug delivery system halloysite nanotubes

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
29 Sep 2022
Historique:
received: 02 08 2022
revised: 16 08 2022
accepted: 19 08 2022
entrez: 14 10 2022
pubmed: 15 10 2022
medline: 18 10 2022
Statut: epublish

Résumé

The use of synthetic materials and the attention towards environmental hazards and toxicity impose the development of green composites with natural origins. Clay is one of the candidates for this approach. Halloysite is a natural clay mineral, a member of the Kaolin group, with characteristic tubular morphology, usually named halloysite nanotubes (HNTs). The different surface chemistry of halloysite allows the selective modification of both the external surface and the inner lumen by supramolecular or covalent interactions. An interesting aspect of HNTs is related to the possibility of introducing different species that can be released more slowly compared to the pristine compound. Due to their unique hollow morphology and large cavity, HNTs can be employed as an optimal natural nanocarrier. This review discusses the structure, properties, and application of HNTs in the biological field, highlighting their high biocompatibility, and analyse the opportunity to use new HNT hybrids as drug carriers and delivery systems.

Identifiants

pubmed: 36232811
pii: ijms231911518
doi: 10.3390/ijms231911518
pmc: PMC9570192
pii:
doi:

Substances chimiques

Drug Carriers 0
Minerals 0
Kaolin 24H4NWX5CO
Clay T1FAD4SS2M

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

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Auteurs

Giuseppa Biddeci (G)

Institute for Innovation and Biomedical Research (IRIB), 90146 Palermo, CNR, Italy.

Gaetano Spinelli (G)

Institute for Innovation and Biomedical Research (IRIB), 90146 Palermo, CNR, Italy.

Paolo Colomba (P)

Institute for Innovation and Biomedical Research (IRIB), 90146 Palermo, CNR, Italy.

Francesco Di Blasi (F)

Institute for Innovation and Biomedical Research (IRIB), 90146 Palermo, CNR, Italy.

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Classifications MeSH