Antiskin Aging Effects of Indole Alkaloid
Humans
Ginkgo biloba
/ metabolism
Tumor Necrosis Factor-alpha
/ metabolism
Matrix Metalloproteinase 1
/ metabolism
Interleukin-6
/ metabolism
Glycosides
/ pharmacology
Cyclooxygenase 2
/ metabolism
Interleukin-8
/ genetics
Fruit
/ metabolism
Proto-Oncogene Proteins c-akt
/ metabolism
Fibroblasts
Cytokines
/ genetics
Collagen
/ metabolism
Indole Alkaloids
/ pharmacology
Esters
/ metabolism
TNF-α
antiskin aging
ginkgo fruitsi
human dermal fibroblasts
indole alkaloid N-glycoside
Journal
Journal of agricultural and food chemistry
ISSN: 1520-5118
Titre abrégé: J Agric Food Chem
Pays: United States
ID NLM: 0374755
Informations de publication
Date de publication:
26 Oct 2022
26 Oct 2022
Historique:
pubmed:
18
10
2022
medline:
28
10
2022
entrez:
17
10
2022
Statut:
ppublish
Résumé
Human skin aging has internal and external factors, both of which are characterized by TNF-α overproduction. Therefore, we aimed to identify a natural product that suppresses the damage that occurs in cutaneous dermal fibroblasts exposed to TNF-α. The protective effects of the indole alkaloid
Identifiants
pubmed: 36251736
doi: 10.1021/acs.jafc.2c05769
doi:
Substances chimiques
Tumor Necrosis Factor-alpha
0
Matrix Metalloproteinase 1
EC 3.4.24.7
Interleukin-6
0
Glycosides
0
Cyclooxygenase 2
EC 1.14.99.1
Interleukin-8
0
Proto-Oncogene Proteins c-akt
EC 2.7.11.1
Cytokines
0
Collagen
9007-34-5
Indole Alkaloids
0
Esters
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM