A case of VIPoma.


Journal

International journal of obstetric anesthesia
ISSN: 1532-3374
Titre abrégé: Int J Obstet Anesth
Pays: Netherlands
ID NLM: 9200430

Informations de publication

Date de publication:
11 2022
Historique:
received: 25 04 2022
revised: 25 08 2022
accepted: 23 09 2022
pubmed: 18 10 2022
medline: 16 11 2022
entrez: 17 10 2022
Statut: ppublish

Résumé

This case report addresses the management of a pregnant woman in the peripartum period with a VIPoma. This rare and highly malignant neuroendocrine tumour secretes vasoactive intestinal peptide (VIP), a substance that may cause potentially life-threatening disruption to physiology. A 36-year-old woman presented for induction of labour with a three-year history of chronic diarrhoea, hypophosphataemia, palpitations and skin flushing. Raised VIP levels indicated presence of a VIPoma, however despite extensive investigation prior to pregnancy by neuroendocrine specialists, the tumour location remained unidentified. The patient delivered a healthy boy with the aid of forceps in theatre following an epidural top-up. Key features of management were a multidisciplinary approach, avoidance of triggers for VIP secretion, strict management of electrolytes and avoidance of severe changes in sympathetic tone during labour with epidural analgesia.

Identifiants

pubmed: 36252446
pii: S0959-289X(22)00315-6
doi: 10.1016/j.ijoa.2022.103600
pii:
doi:

Substances chimiques

Vasoactive Intestinal Peptide 37221-79-7

Types de publication

Case Reports

Langues

eng

Sous-ensembles de citation

IM

Pagination

103600

Informations de copyright

Copyright © 2022 Elsevier Ltd. All rights reserved.

Auteurs

L Crawford (L)

Russells Hall Hospital, Pensnett Road, Dudley, West Midlands, UK. Electronic address: louise.crawford5@nhs.net.

V Amin (V)

Russells Hall Hospital, Pensnett Road, Dudley, West Midlands, UK.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH