A case of VIPoma.
Neuroendocrine tumour
Pregnancy
VIPoma
Journal
International journal of obstetric anesthesia
ISSN: 1532-3374
Titre abrégé: Int J Obstet Anesth
Pays: Netherlands
ID NLM: 9200430
Informations de publication
Date de publication:
11 2022
11 2022
Historique:
received:
25
04
2022
revised:
25
08
2022
accepted:
23
09
2022
pubmed:
18
10
2022
medline:
16
11
2022
entrez:
17
10
2022
Statut:
ppublish
Résumé
This case report addresses the management of a pregnant woman in the peripartum period with a VIPoma. This rare and highly malignant neuroendocrine tumour secretes vasoactive intestinal peptide (VIP), a substance that may cause potentially life-threatening disruption to physiology. A 36-year-old woman presented for induction of labour with a three-year history of chronic diarrhoea, hypophosphataemia, palpitations and skin flushing. Raised VIP levels indicated presence of a VIPoma, however despite extensive investigation prior to pregnancy by neuroendocrine specialists, the tumour location remained unidentified. The patient delivered a healthy boy with the aid of forceps in theatre following an epidural top-up. Key features of management were a multidisciplinary approach, avoidance of triggers for VIP secretion, strict management of electrolytes and avoidance of severe changes in sympathetic tone during labour with epidural analgesia.
Identifiants
pubmed: 36252446
pii: S0959-289X(22)00315-6
doi: 10.1016/j.ijoa.2022.103600
pii:
doi:
Substances chimiques
Vasoactive Intestinal Peptide
37221-79-7
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
103600Informations de copyright
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