Rhodotorula sp.-based biorefinery: a source of valuable biomolecules.

Rhodotorula / genetics Biomass Carotenoids Genetic Engineering Biofuels
Biorefinery Carotenoids Enzymes, Circular bioeconomy Lipids Rhodotorula Yeast

Journal

Applied microbiology and biotechnology
ISSN: 1432-0614
Titre abrégé: Appl Microbiol Biotechnol
Pays: Germany
ID NLM: 8406612

Informations de publication

Date de publication:
Nov 2022
Historique:
received: 29 07 2022
accepted: 27 09 2022
revised: 26 09 2022
pubmed: 19 10 2022
medline: 19 11 2022
entrez: 18 10 2022
Statut: ppublish

Résumé

The development of an effective, realistic, and sustainable microbial biorefinery depends on several factors, including as one of the key aspects an adequate selection of microbial strain. The oleaginous red yeast Rhodotorula sp. has been studied as one powerful source for a plethora of high added-value biomolecules, such as carotenoids, lipids, and enzymes. Although known for over a century, the use of Rhodotorula sp. as resource for valuable products has not yet commercialized. Current interests for Rhodotorula sp. yeast have sparked from its high nutritional versatility and ability to convert agro-food residues into added-value biomolecules, two attractive characteristics for designing new biorefineries. In addition, as for other yeast-based bioprocesses, the overall process sustainability can be maximized by a proper integration with subsequent downstream processing stages, for example, by using eco-friendly solvents for the recovery of intracellular products from yeast biomass. This review intends to reflect on the current state of the art of microbial bioprocesses using Rhodotorula species. Therefore, we will provide an analysis of bioproduction performance with some insights regarding downstream separation steps for the extraction of high added-value biomolecules (specifically using efficient and sustainable platforms), providing information regarding the potential applications of biomolecules produced by Rhodotorula sp, as well as detailing the strengths and limitations of yeast-based biorefinery approaches. Novel genetic engineering technologies are further discussed, indicating some directions on their possible use for maximizing the potential of Rhodotorula sp. as cell factories. KEY POINTS: • Rhodotorula sp. are valuable source of high value-added compounds. • Potential of employing Rhodotorula sp. in a multiple product biorefinery. • Future perspectives in the biorefining of Rhodotorula sp. were discussed.

Identifiants

DOI: 10.1007/s00253-022-12221-5 PMID: 36255447
pubmed: 36255447
doi: 10.1007/s00253-022-12221-5
pii: 10.1007/s00253-022-12221-5
doi:

Substances chimiques

Carotenoids 36-88-4
Biofuels 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

7431-7447

Subventions

Organisme : FAPESP
ID : 2020/08655-0
Organisme : FAPESP
ID : 2019/15493-9
Organisme : FAPESP
ID : 2018/06908-8

Informations de copyright

© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

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Auteurs

Cassamo U Mussagy (CU)

Escuela de Agronomía, Facultad de Ciencias Agronómicas y de los Alimentos, Pontificia Universidad Católica de Valparaíso, 2260000, Quillota, Chile. cassamo.mussagy@pucv.cl.
ORCID: 0000-0003-2907-5826

Helena F Ribeiro (HF)

Department of Chemical Engineering, CIEPQPF, University of Coimbra, Rua Sílvio Lima, Pólo II - Pinhal de Marrocos, 3030-790, Coimbra, Portugal.

Valeria C Santos-Ebinuma (VC)

Department of Engineering of Bioprocesses and Biotechnology, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, SP, 14800-903, Brazil.

Boelo Schuur (B)

Sustainable Process Technology Group, Process and Catalysis Engineering Cluster, Faculty of Science and Technology, University of Twente, PO Box 217, 7500, Enschede, AE, Netherlands.

Jorge F B Pereira (JFB)

Department of Chemical Engineering, CIEPQPF, University of Coimbra, Rua Sílvio Lima, Pólo II - Pinhal de Marrocos, 3030-790, Coimbra, Portugal. jfbpereira@eq.uc.pt.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Champignons › Levures › Rhodotorula › Rhodotorula sp.-based biorefinery: a source of...
questionsmedicales.fr › Environnement et santé publique › Environnement › Écosystème › Biomasse › Rhodotorula sp.-based biorefinery: a source of...
questionsmedicales.fr › Facteurs biologiques › Pigments biologiques › Caroténoïdes › Rhodotorula sp.-based biorefinery: a source of...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Génie génétique › Rhodotorula sp.-based biorefinery: a source of...
questionsmedicales.fr › Environnement et santé publique › Environnement › Ressources de production d'énergie › Énergie renouvelable › Biocarburants › Rhodotorula sp.-based biorefinery: a source of...