Transition matrices model as a way to better understand and predict intra-hospital pathways of covid-19 patients.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
20 10 2022
Historique:
received: 17 02 2022
accepted: 11 10 2022
entrez: 20 10 2022
pubmed: 21 10 2022
medline: 25 10 2022
Statut: epublish

Résumé

Since January 2020, the SARS-CoV-2 pandemic has severely affected hospital systems worldwide. In Europe, the first 3 epidemic waves (periods) have been the most severe in terms of number of infected and hospitalized patients. There are several descriptions of the demographic and clinical profiles of patients with COVID-19, but few studies of their hospital pathways. We used transition matrices, constructed from Markov chains, to illustrate the transition probabilities between different hospital wards for 90,834 patients between March 2020 and July 2021 managed in Paris area. We identified 3 epidemic periods (waves) during which the number of hospitalized patients was significantly high. Between the 3 periods, the main differences observed were: direct admission to ICU, from 14 to 18%, mortality from ICU, from 28 to 24%, length of stay (alive patients), from 9 to 7 days from CH and from 18 to 10 days from ICU. The proportion of patients transferred from CH to ICU remained stable. Understanding hospital pathways of patients is crucial to better monitor and anticipate the impact of SARS-CoV-2 pandemic on health system.

Identifiants

pubmed: 36266423
doi: 10.1038/s41598-022-22227-8
pii: 10.1038/s41598-022-22227-8
pmc: PMC9584905
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

17508

Informations de copyright

© 2022. The Author(s).

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Auteurs

Arnaud Foucrier (A)

Ile-de-France Regional Health Agency, Paris, France. arnaud.foucrier@aphp.fr.
Hôpital Beaujon, DMU PARABOL, University of Paris, APHP, Paris, France. arnaud.foucrier@aphp.fr.

Jules Perrio (J)

Data Science and Analytics Department, SESAN, Paris, France.

Johann Grisel (J)

Data Science and Analytics Department, SESAN, Paris, France.

Pascal Crépey (P)

Ecole des Hautes Etudes en Santé Publique, REPERES (Recherche en Pharmaco-Epidémiologie et Recours Aux Soins), University of Rennes, EA 7449, Rennes, France.

Etienne Gayat (E)

Department of Anaesthesiology and Critical Care, Hôpital Lariboisière, DMU PARABOL, University of Paris, Paris, France.
Inserm UMR-S 942, Cardiovascular Markers in Stress Conditions (MASCOT), University of Paris, Paris, France.

Antoine Vieillard-Baron (A)

University Hospital Ambroise Paré, APHP, Boulogne-Billancourt, and Université de Versailles Saint Quentin en Yvelines UMR 1018, Boulogne-Billancourt, France.

Frédéric Batteux (F)

Institut Cochin, INSERM U1016, Université Paris Descartes, Sorbonne Paris Cité, Paris, France.

Tobias Gauss (T)

Grenoble Alpes Trauma Centre, Pôle Anesthésie-Réanimation, CHU de Grenoble, La Tronche, France.

Pierre Squara (P)

Department of Intensive Care and Cardiology, Clinique Ambroise Paré, Neuilly-Sur-Seine, France.

Seak-Hy Lo (SH)

Ile-de-France Regional Health Agency, Paris, France.

Matthias Wargon (M)

Emergency Department, Hôpital Delafontaine, Saint-Denis, France.
Observatoire Regional Des Soins Non Programmés-Ile-de-France, Saint-Denis, France.

Romain Hellmann (R)

Ile-de-France Regional Health Agency, Paris, France.
Emergency Department, Bichat Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.

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