Prenatal diagnosis of vermian cyst: a new type of posterior fossa cyst.


Journal

Pediatric radiology
ISSN: 1432-1998
Titre abrégé: Pediatr Radiol
Pays: Germany
ID NLM: 0365332

Informations de publication

Date de publication:
03 2023
Historique:
received: 13 07 2022
accepted: 03 10 2022
revised: 25 08 2022
pubmed: 24 10 2022
medline: 3 3 2023
entrez: 23 10 2022
Statut: ppublish

Résumé

Prenatal diagnoses of cystic malformations of the posterior fossa mainly encompass arachnoid cysts, Blake's pouch cysts and Dandy-Walker syndrome. To date, vermian cysts have not been reported prenatally. To report a series of fetuses with a vermian cyst. This was a single-center retrospective study conducted from 2012 to 2021. We included all fetuses presenting with a vermian cyst and excluded all other types of posterior fossa cyst. The cyst was visible at prenatal ultrasound (US) and/or magnetic resonance imaging (MRI). Postnatal imaging and/or clinical outcome data were available. Sixteen fetuses fulfilled the inclusion criteria with a strong female predominance (n=13). US and MRI were performed at a mean gestational age of 29+5 and 33+1 weeks, respectively. In all patients, the cyst was in the vermian horizontal fissure. The mean longest dimension was about 10 mm. The vermis and other posterior fossa structures were otherwise normal. At postnatal imaging, 13 children underwent brain imaging including 11 MRIs with complete regression (n=9), stability (n=1) and increase in size (n=3) of the cyst. Psychomotor development was normal in 14 children. One child (with an inner ear malformation) showed a slight delay in walking and language acquisition. Slight walking ataxia was present in another child. We report 16 fetuses with posterior fossa cysts located within the vermis at the level of the horizontal fissure, diagnosed at US and/or MRI and carrying an overall excellent neurological prognosis.

Sections du résumé

BACKGROUND
Prenatal diagnoses of cystic malformations of the posterior fossa mainly encompass arachnoid cysts, Blake's pouch cysts and Dandy-Walker syndrome. To date, vermian cysts have not been reported prenatally.
OBJECTIVES
To report a series of fetuses with a vermian cyst.
MATERIALS AND METHODS
This was a single-center retrospective study conducted from 2012 to 2021. We included all fetuses presenting with a vermian cyst and excluded all other types of posterior fossa cyst. The cyst was visible at prenatal ultrasound (US) and/or magnetic resonance imaging (MRI). Postnatal imaging and/or clinical outcome data were available.
RESULTS
Sixteen fetuses fulfilled the inclusion criteria with a strong female predominance (n=13). US and MRI were performed at a mean gestational age of 29+5 and 33+1 weeks, respectively. In all patients, the cyst was in the vermian horizontal fissure. The mean longest dimension was about 10 mm. The vermis and other posterior fossa structures were otherwise normal. At postnatal imaging, 13 children underwent brain imaging including 11 MRIs with complete regression (n=9), stability (n=1) and increase in size (n=3) of the cyst. Psychomotor development was normal in 14 children. One child (with an inner ear malformation) showed a slight delay in walking and language acquisition. Slight walking ataxia was present in another child.
CONCLUSION
We report 16 fetuses with posterior fossa cysts located within the vermis at the level of the horizontal fissure, diagnosed at US and/or MRI and carrying an overall excellent neurological prognosis.

Identifiants

pubmed: 36274068
doi: 10.1007/s00247-022-05531-3
pii: 10.1007/s00247-022-05531-3
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

461-469

Informations de copyright

© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Références

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Auteurs

Justine Chanclud (J)

Department of Pediatric Radiology, Trousseau Hospital, APHP Sorbonne Université, 26 avenue du Docteur Arnold Netter, 75012, Paris, France. justine.chanclud@hotmail.fr.

Stéphanie Valence (S)

Department of Pediatric Neurology, Trousseau Hospital, APHP Sorbonne Université, 26 avenue du Docteur Arnold Netter, 75012, Paris, France.

Saskia Vande Perre (SV)

Department of Pediatric Radiology, Trousseau Hospital, APHP Sorbonne Université, 26 avenue du Docteur Arnold Netter, 75012, Paris, France.

Lucie Guilbaud (L)

Department of Fetal Medecine, GRC Image, APHP Sorbonne Université, 26 avenue du Docteur Arnold Netter, 75012, Paris, France.

Marie-Laure Moutard (ML)

Department of Pediatric Neurology, Trousseau Hospital, APHP Sorbonne Université, 26 avenue du Docteur Arnold Netter, 75012, Paris, France.

Jean-Marie Jouannic (JM)

Department of Fetal Medecine, GRC Image, APHP Sorbonne Université, 26 avenue du Docteur Arnold Netter, 75012, Paris, France.

Hubert Ducou Le Pointe (H)

Department of Pediatric Radiology, Trousseau Hospital, APHP Sorbonne Université, 26 avenue du Docteur Arnold Netter, 75012, Paris, France.

Eléonore Blondiaux (E)

Department of Pediatric Radiology, Trousseau Hospital, APHP Sorbonne Université, 26 avenue du Docteur Arnold Netter, 75012, Paris, France.

Catherine Garel (C)

Department of Pediatric Radiology, Trousseau Hospital, APHP Sorbonne Université, 26 avenue du Docteur Arnold Netter, 75012, Paris, France.

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