A non-traditional crystal-based compound screening method targeting the ATP binding site of
GRP78
Plasmodium falciparum
chaperone
drug discovery & development
malaria
nucleoside analogues
unfolded protein response
Journal
Frontiers in molecular biosciences
ISSN: 2296-889X
Titre abrégé: Front Mol Biosci
Pays: Switzerland
ID NLM: 101653173
Informations de publication
Date de publication:
2022
2022
Historique:
received:
29
05
2022
accepted:
03
08
2022
entrez:
24
10
2022
pubmed:
25
10
2022
medline:
25
10
2022
Statut:
epublish
Résumé
Drug resistance to front-line malarial treatments represents an ongoing threat to control malaria, a vector borne infectious disease. The malarial parasite,
Identifiants
pubmed: 36275624
doi: 10.3389/fmolb.2022.956095
pii: 956095
pmc: PMC9585173
doi:
Types de publication
Journal Article
Langues
eng
Pagination
956095Informations de copyright
Copyright © 2022 Mrozek, Antoshchenko, Chen, Zepeda-Velázquez, Smil, Kumar, Lu and Park.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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