Gastric dilatation in patients with restrictive eating disorders.
anorexia nervosa
avoidant/restrictive food intake disorder
eating disorders
gastric dilatation
gastric dimension
malnutrition
Journal
The International journal of eating disorders
ISSN: 1098-108X
Titre abrégé: Int J Eat Disord
Pays: United States
ID NLM: 8111226
Informations de publication
Date de publication:
12 2022
12 2022
Historique:
revised:
12
10
2022
received:
29
06
2022
accepted:
14
10
2022
pubmed:
27
10
2022
medline:
15
12
2022
entrez:
26
10
2022
Statut:
ppublish
Résumé
To better understand gastric dimensions in patients diagnosed with restrictive eating disorders (EDs). In this retrospective study, 56 patients, with restrictive EDs, and 60 gender/age/race-matched patients from an outpatient clinic, were studied. Difference in stomach size, between cohorts, was ascertained, and regression analyses were used to examine associations with stomach size in the ED cohort. Patients with EDs were found to have significantly enlarged gastric dimensions when compared to the control group (M:14.8 cm [SD: 3.2] vs. 11.4 cm [SD: 2.9], p < .0001). Among the ED cohort, blood urea nitrogen (BUN), on the day of imaging, positively correlated with gastric dimensions (r = .43, p = .0009), while hypoalbuminemia negatively correlated with gastric dimensions (r = -.37, p = .005). BUN and albumin nadir were also significantly associated with stomach size (r Findings in this study suggest that malnutrition, secondary to EDs, may be associated with an enlarged stomach. The relationship between the gastric dimensions and reported GI symptoms in this population remain to be determined. There are many physiologic changes to the gastrointestinal system that develop with malnutrition but the contribution of these physiologic changes toward the reported GI symptoms and refeeding difficulties is unclear. This is the first study to suggest that patients with malnutrition, secondary to EDs, may be associated with an enlarged stomach, and this potential relationship requires further investigation.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1853-1858Informations de copyright
© 2022 Wiley Periodicals LLC.
Références
American Pschiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). APA.
Di Stefano, M., Miceli, E., Mazzocchi, S., Tana, P., & Corazza, G. R. (2005). The role of gastric accommodation in the pathophysiology of functional dyspepsia. European Review for Medical and Pharmacological Sciences, 9(5 Suppl 1), 23-28.
Gibson, D., Watters, A., & Mehler, P. S. (2021). The intersect of gastrointestinal symptoms and malnutrition associated with anorexia nervosa and avoidant/restrictive food intake disorder: Functional or pathophysiologic?-A systematic review. The International Journal of Eating Disorders, 54(6), 1019-1054. https://doi.org/10.1002/eat.23553
Gyurkovics, E., Tihanyi, B., Szijarto, A., Kaliszky, P., Temesi, V., Sas, H., & Kupcsulik, P. (2006). Fatal outcome from extreme acute gastric dilation after an eating binge. The International Journal of Eating Disorders, 39(7), 602-605. https://doi.org/10.1002/eat.20281
Krantz, M. J., Lee, D., Donahoo, W. T., & Mehler, P. S. (2005). The paradox of normal serum albumin in anorexia nervosa: A case report. International Journal of Eating Disorders, 37(3), 278-280. https://doi.org/10.1002/eat.20129
Mascolo, M., Dee, E., Townsend, R., Brinton, J. T., & Mehler, P. S. (2015). Severe gastric dilatation due to superior mesenteric artery syndrome in anorexia nervosa. The International Journal of Eating Disorders, 48(5), 532-534. https://doi.org/10.1002/eat.22385
Panyko, A., Vician, M., & Dubovský, M. (2020). Massive acute gastric dilatation in a patient with anorexia nervosa. Journal of Gastrointestinal Surgery, 25(3), 856-858. https://doi.org/10.1007/s11605-020-04715-2
Pitre, T., Mah, J., Vertes, J., & Tugwell, B. (2021). Acute gastric dilatation in a patient with severe anorexia nervosa: A case report. Journal of Medical Case Reports, 15(1), 61. https://doi.org/10.1186/s13256-020-02575-7
Simrén, M., Törnblom, H., Palsson, O. S., van Tilburg, M. A. L., Van Oudenhove, L., Tack, J., & Whitehead, W. E. (2018). Visceral hypersensitivity is associated with GI symptom severity in functional GI disorders: Consistent findings from five different patient cohorts. Gut, 67(2), 255-262. https://doi.org/10.1136/gutjnl-2016-312361
Soeters, P. B., Wolfe, R. R., & Shenkin, A. (2019). Hypoalbuminemia: Pathogenesis and clinical significance. JPEN Journal of Parenteral and Enteral Nutrition, 43(2), 181-193. https://doi.org/10.1002/jpen.1451
Tweed-Kent, A. M., Fagenholz, P. J., & Alam, H. B. (2010). Acute gastric dilatation in a patient with anorexia nervosa binge/purge subtype. Journal of Emergencies, Trauma, and Shock, 3(4), 403-405. https://doi.org/10.4103/0974-2700.70774
Vettoretto, N., Viotti, F., Taglietti, L., & Giovanetti, M. (2010). Acute idiopathic gastric necrosis, perforation and shock. Journal of Emergencies, Trauma and Shock, 3(3), 304. https://doi.org/10.4103/0974-2700.66564