Lynch Syndrome Identification in Saudi Cohort of Endometrial Cancer Patients Screened by Universal Approach.
Lynch syndrome
Lynch-like syndrome
endometrial cancer
germline mutations
mismatch repair-deficient
somatic mutations
universal screening
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
14 Oct 2022
14 Oct 2022
Historique:
received:
06
09
2022
revised:
08
10
2022
accepted:
12
10
2022
entrez:
27
10
2022
pubmed:
28
10
2022
medline:
29
10
2022
Statut:
epublish
Résumé
Lynch syndrome (LS) is the most common cause of inherited endometrial cancer (EC). The prevalence and molecular characteristic of LS in Middle Eastern women with EC have been underexplored. To evaluate the frequency of LS in a cohort of EC patients from Saudi Arabia, a total of 436 EC cases were screened utilizing immunohistochemistry (IHC),
Identifiants
pubmed: 36293153
pii: ijms232012299
doi: 10.3390/ijms232012299
pmc: PMC9603045
pii:
doi:
Substances chimiques
MutS Homolog 2 Protein
EC 3.6.1.3
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Références
BMC Bioinformatics. 2020 Dec 10;21(1):571
pubmed: 33302872
Gut. 2009 Jan;58(1):90-6
pubmed: 18832519
Gynecol Oncol. 2017 Nov;147(2):388-395
pubmed: 28847642
Int J Cancer. 2016 Sep 1;139(5):1091-7
pubmed: 27082205
Hum Genet. 2017 Nov;136(11-12):1431-1444
pubmed: 28975465
Gynecol Oncol. 2017 Aug;146(2):217-224
pubmed: 28596016
Int J Cancer. 2016 Apr 15;138(8):1928-35
pubmed: 26620301
CA Cancer J Clin. 2018 Nov;68(6):394-424
pubmed: 30207593
Radiographics. 2018 Mar-Apr;38(2):483-499
pubmed: 29528821
J Clin Endocrinol Metab. 2011 Jan;96(1):E215-24
pubmed: 20926535
World J Gastroenterol. 2015 Aug 21;21(31):9253-61
pubmed: 26309352
Bioinformatics. 2012 Sep 15;28(18):i333-i339
pubmed: 22962449
Bioinformatics. 2009 Jul 15;25(14):1754-60
pubmed: 19451168
Genet Med. 2019 Oct;21(10):2167-2180
pubmed: 31086306
Cancer Res. 2000 Sep 15;60(18):5021-6
pubmed: 11016622
J Clin Oncol. 2015 Dec 20;33(36):4301-8
pubmed: 26552419
J Natl Cancer Inst. 2018 Apr 1;110(4):354-361
pubmed: 29045681
JCI Insight. 2020 Sep 17;5(18):
pubmed: 32841224
J Pathol. 2007 Oct;213(2):190-9
pubmed: 17703498
Annu Rev Genomics Hum Genet. 2019 Aug 31;20:293-307
pubmed: 30848956
Gynecol Oncol. 2020 Oct;159(1):229-238
pubmed: 32694065
Nucleic Acids Res. 2010 Sep;38(16):e164
pubmed: 20601685
Ann Oncol. 2017 Jan 1;28(1):96-102
pubmed: 27742654
BJOG. 2021 Mar;128(4):728-736
pubmed: 32725920
Nat Commun. 2018 Oct 2;9(1):4038
pubmed: 30279509
Cancer Epidemiol Biomarkers Prev. 1996 Jun;5(6):411-7
pubmed: 8781735
Cancer Res. 2001 Apr 15;61(8):3410-8
pubmed: 11309301
Gynecol Oncol. 2021 Jan;160(1):161-168
pubmed: 33393477
PLoS One. 2014 Jan 21;9(1):e86657
pubmed: 24466191
J Clin Endocrinol Metab. 2008 Feb;93(2):611-8
pubmed: 18000091