Bifidobacterium animalis Promotes the Growth of Weaning Piglets by Improving Intestinal Development, Enhancing Antioxidant Capacity, and Modulating Gut Microbiota.


Journal

Applied and environmental microbiology
ISSN: 1098-5336
Titre abrégé: Appl Environ Microbiol
Pays: United States
ID NLM: 7605801

Informations de publication

Date de publication:
22 11 2022
Historique:
pubmed: 28 10 2022
medline: 25 11 2022
entrez: 27 10 2022
Statut: ppublish

Résumé

Probiotics are widely used to promote performance and improve gut health in weaning piglets. Therefore, the objective of this study was to investigate the effects of dietary supplementation with Bifidobacterium animalis subsp. lactis (B. animalis) JYBR-190 on the growth performance, intestine health, and gut microbiota of weaning piglets. The results showed that the dietary addition of B. animalis significantly improved growth performance and decreased diarrhea incidence. B. animalis increased villus height in the duodenum and elevated goblet cell numbers and amylase activity in the jejunum. Additionally, B. animalis supplementation markedly increased total antioxidant capacity in jejunal mucosa but declined the malondialdehyde content. B. animalis treatment did not affect the mRNA expressions associated with the intestinal barrier and inflammatory cytokine in various intestinal segments. Microbiota analysis indicated that a diet supplemented with B. animalis significantly increased the relative abundances of health-promoting bacteria in the lumen, such as Streptococcus

Identifiants

pubmed: 36300953
doi: 10.1128/aem.01296-22
pmc: PMC9680619
doi:

Substances chimiques

Antioxidants 0
Anti-Bacterial Agents 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0129622

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Auteurs

Jiaman Pang (J)

State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural Universitygrid.22935.3f, Beijing, China.

Yisi Liu (Y)

State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural Universitygrid.22935.3f, Beijing, China.

Luyuan Kang (L)

State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural Universitygrid.22935.3f, Beijing, China.

Hao Ye (H)

State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural Universitygrid.22935.3f, Beijing, China.
Adaptation Physiology Group, Department of Animal Sciences, Wageningen University and Research, Wageningen, The Netherlands.

Jianjun Zang (J)

State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural Universitygrid.22935.3f, Beijing, China.

Junjun Wang (J)

State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural Universitygrid.22935.3f, Beijing, China.

Dandan Han (D)

State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural Universitygrid.22935.3f, Beijing, China.

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Classifications MeSH