Triple Diagnosis of Attention-Deficit/Hyperactivity Disorder with Coexisting Bipolar and Alcohol Use Disorders: Clinical Aspects and Pharmacological Treatments.

ADHD alcohol use disorder bipolar disorder lithium neurodevelopment triple diagnosis valproic acid

Journal

Current neuropharmacology
ISSN: 1875-6190
Titre abrégé: Curr Neuropharmacol
Pays: United Arab Emirates
ID NLM: 101157239

Informations de publication

Date de publication:
2023
Historique:
received: 13 05 2022
revised: 13 06 2022
accepted: 03 08 2022
medline: 22 5 2023
pubmed: 29 10 2022
entrez: 28 10 2022
Statut: ppublish

Résumé

Attention-Deficit/Hyperactivity Disorder (ADHD), Bipolar Disorder (BD) and Alcohol Use Disorder (AUD) are common medical conditions often coexisting and exerting mutual influence on disease course and pharmacological treatment response. Each disorder, when considered separately, relies on different therapeutic approaches, making it crucial to detect the plausible association between them. Treating solely the emerging condition (e.g., alcoholism) and disregarding the patient's whole psychopathological ground often leads to treatment failure and relapse. Clinical experience and scientific evidence rather show that tailoring treatments for these three conditions considering their co-occurrence as a sole complex disorder yields more fulfilling and durable clinical outcomes. In light of the above considerations, the purpose of the present review is to critically discuss the pharmacological strategies in the personalized treatment of complex conditions defined by ADHD-bipolarityalcoholism coexistence.

Identifiants

pubmed: 36306451
pii: CN-EPUB-126017
doi: 10.2174/1570159X20666220830154002
pmc: PMC10472804
doi:

Types de publication

Review Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1467-1476

Informations de copyright

Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

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Auteurs

Francesco Weiss (F)

Psychiatry Unit 2, Department of Clinical and Experimental Medicine, Faculty of Medicine and Surgery, University of Pisa, Pisa, Italy.

Simone Tidona (S)

Psychiatry Unit 2, Department of Clinical and Experimental Medicine, Faculty of Medicine and Surgery, University of Pisa, Pisa, Italy.

Marco Carli (M)

Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa 56126, Italy.

Giulio Perugi (G)

Psychiatry Unit 2, Department of Clinical and Experimental Medicine, Faculty of Medicine and Surgery, University of Pisa, Pisa, Italy.

Marco Scarselli (M)

Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa 56126, Italy.

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