Microaerobic metabolism of lactate and propionate enhances vitamin B
Propionate
Propionibacterium freudenreichii
Respiration
Vitamin B12
Wood-Werkman cycle
Journal
Microbial cell factories
ISSN: 1475-2859
Titre abrégé: Microb Cell Fact
Pays: England
ID NLM: 101139812
Informations de publication
Date de publication:
28 Oct 2022
28 Oct 2022
Historique:
received:
22
07
2022
accepted:
02
10
2022
entrez:
29
10
2022
pubmed:
30
10
2022
medline:
2
11
2022
Statut:
epublish
Résumé
Propionibacterium freudenreichii is used in biotechnological applications to produce vitamin B Here we show biomass formation increases 2.7 times for P. freudenreichii grown in microaerobic conditions on lactate versus anaerobic conditions (1.87 g/L vs 0.70 g/L). Consumption of lactate in microaerobic conditions resulted first in production of pyruvate, propionate and acetate. When lactate was depleted, pyruvate and propionate were oxidised with a concomitant sixfold increase in the B Here we have shown both B
Sections du résumé
BACKGROUND
BACKGROUND
Propionibacterium freudenreichii is used in biotechnological applications to produce vitamin B
RESULTS
RESULTS
Here we show biomass formation increases 2.7 times for P. freudenreichii grown in microaerobic conditions on lactate versus anaerobic conditions (1.87 g/L vs 0.70 g/L). Consumption of lactate in microaerobic conditions resulted first in production of pyruvate, propionate and acetate. When lactate was depleted, pyruvate and propionate were oxidised with a concomitant sixfold increase in the B
CONCLUSIONS
CONCLUSIONS
Here we have shown both B
Identifiants
pubmed: 36307780
doi: 10.1186/s12934-022-01945-8
pii: 10.1186/s12934-022-01945-8
pmc: PMC9617374
doi:
Substances chimiques
Propionates
0
Vitamin B 12
P6YC3EG204
Lactic Acid
33X04XA5AT
Pyruvates
0
Vitamins
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
225Informations de copyright
© 2022. The Author(s).
Références
Environ Microbiol. 2021 Jun;23(6):3116-3129
pubmed: 33955639
Bioresour Technol. 2012 Jan;104:652-9
pubmed: 22082511
Biotechnol Prog. 1999 Mar-Apr;15(2):201-7
pubmed: 10194395
J Gen Microbiol. 1972 Aug;71(3):515-24
pubmed: 4647470
Biochem Eng J. 2000 Dec 1;6(3):207-214
pubmed: 11080651
Mol Microbiol. 2001 Mar;39(6):1562-71
pubmed: 11260473
Arch Biochem Biophys. 1967 Aug;121(2):304-10
pubmed: 6057100
Microb Cell Fact. 2015 Nov 23;14:186
pubmed: 26597297
Appl Environ Microbiol. 2010 Sep;76(17):5791-801
pubmed: 20639365
PLoS One. 2010 Jul 23;5(7):e11748
pubmed: 20668525
Appl Microbiol Biotechnol. 2015 Dec;99(24):10481-8
pubmed: 26373724
Microb Cell Fact. 2022 Mar 26;21(1):48
pubmed: 35346203
Genes (Basel). 2020 Sep 23;11(10):
pubmed: 32977700
Biochem J. 1989 Jun 1;260(2):345-52
pubmed: 2569861
Appl Microbiol Biotechnol. 2002 Mar;58(3):275-85
pubmed: 11935176
Microbiology (Reading). 2002 Jun;148(Pt 6):1845-1853
pubmed: 12055304
Biochim Biophys Acta. 2011 Nov;1807(11):1398-413
pubmed: 21756872
J Bacteriol. 2019 Jun 10;201(13):
pubmed: 30988035
Bioresour Technol. 2012 Feb;105:128-33
pubmed: 22178491
Biochem Soc Trans. 2012 Jun 1;40(3):581-6
pubmed: 22616870
Nat Rev Microbiol. 2021 Dec;19(12):774-785
pubmed: 34183820
J Biotechnol. 2010 Jul 20;148(2-3):139-43
pubmed: 20553774
Microb Biotechnol. 2018 Mar;11(2):369-380
pubmed: 29215194
J Dairy Res. 2000 Feb;67(1):65-71
pubmed: 10717844
J Biosci Bioeng. 2004;98(3):167-73
pubmed: 16233685
J Biotechnol. 2015 Jan 10;193:123-9
pubmed: 25455014
Food Microbiol. 2018 Aug;73:216-226
pubmed: 29526206
Antonie Van Leeuwenhoek. 1976;42(3):217-28
pubmed: 1086638