Lipids mediate supramolecular outer membrane protein assembly in bacteria.


Journal

Science advances
ISSN: 2375-2548
Titre abrégé: Sci Adv
Pays: United States
ID NLM: 101653440

Informations de publication

Date de publication:
04 Nov 2022
Historique:
entrez: 2 11 2022
pubmed: 3 11 2022
medline: 5 11 2022
Statut: ppublish

Résumé

β Barrel outer membrane proteins (OMPs) cluster into supramolecular assemblies that give function to the outer membrane (OM) of Gram-negative bacteria. How such assemblies form is unknown. Here, through photoactivatable cross-linking into the

Identifiants

pubmed: 36322653
doi: 10.1126/sciadv.adc9566
pmc: PMC9629720
doi:

Substances chimiques

Escherichia coli Proteins 0
Bacterial Outer Membrane Proteins 0
Lipids 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

eadc9566

Subventions

Organisme : Medical Research Council
ID : MR/R000328/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/V028839/1
Pays : United Kingdom

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Auteurs

Melissa N Webby (MN)

Department of Biochemistry, South Parks Road, University of Oxford, Oxford OX1 3QU, UK.

Abraham O Oluwole (AO)

Physical and Theoretical Chemistry Laboratory, Department of Chemistry, University of Oxford, Oxford OX1 3QZ, UK.
The Kavli Institute for Nanoscience Discovery, South Parks Road, Oxford OX1 3QZ, UK.

Conrado Pedebos (C)

Department of Biochemistry, South Parks Road, University of Oxford, Oxford OX1 3QU, UK.

Patrick G Inns (PG)

Department of Biochemistry, South Parks Road, University of Oxford, Oxford OX1 3QU, UK.

Anna Olerinyova (A)

Physical and Theoretical Chemistry Laboratory, Department of Chemistry, University of Oxford, Oxford OX1 3QZ, UK.

Dheeraj Prakaash (D)

Department of Biochemistry, South Parks Road, University of Oxford, Oxford OX1 3QU, UK.

Nicholas G Housden (NG)

Department of Biochemistry, South Parks Road, University of Oxford, Oxford OX1 3QU, UK.

Georgina Benn (G)

London Centre for Nanotechnology, University College London, London WC1H 0AH, UK.
Institute of Structural and Molecular Biology, University College London, London WC1E 6BT, UK.

Dawei Sun (D)

Structural Biology, Genentech Inc., South San Francisco, USA.

Bart W Hoogenboom (BW)

London Centre for Nanotechnology, University College London, London WC1H 0AH, UK.
Institute of Structural and Molecular Biology, University College London, London WC1E 6BT, UK.
Department of Physics and Astronomy, University College London, WC1E 6BT London, UK.

Philipp Kukura (P)

Physical and Theoretical Chemistry Laboratory, Department of Chemistry, University of Oxford, Oxford OX1 3QZ, UK.

Shabaz Mohammed (S)

Department of Biochemistry, South Parks Road, University of Oxford, Oxford OX1 3QU, UK.
Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford OX1 3QZ, UK.
Mechanistic Proteomics, Rosalind Franklin Institute, Harwell Campus, Didcot OX11 OFA, UK.

Carol V Robinson (CV)

Physical and Theoretical Chemistry Laboratory, Department of Chemistry, University of Oxford, Oxford OX1 3QZ, UK.
The Kavli Institute for Nanoscience Discovery, South Parks Road, Oxford OX1 3QZ, UK.

Syma Khalid (S)

Department of Biochemistry, South Parks Road, University of Oxford, Oxford OX1 3QU, UK.

Colin Kleanthous (C)

Department of Biochemistry, South Parks Road, University of Oxford, Oxford OX1 3QU, UK.

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