Characterization of a polysaccharide from Polygala tenuifolia willd. with immune activity via activation MAPKs pathway.
Immunomodulatory activity
Polygala tenuifolia Willd.
Polysaccharide
Structural characteristic
Journal
Bioorganic chemistry
ISSN: 1090-2120
Titre abrégé: Bioorg Chem
Pays: United States
ID NLM: 1303703
Informations de publication
Date de publication:
01 2023
01 2023
Historique:
received:
25
08
2022
revised:
14
10
2022
accepted:
15
10
2022
pubmed:
5
11
2022
medline:
30
11
2022
entrez:
4
11
2022
Statut:
ppublish
Résumé
Polysaccharides from the Polygala tenuifolia Willd. have been shown multiple biological activities, however the structural feature and immunomodulatory activity are still rarely reported. In this study, a polysaccharide was obtained by purification, and its structural characteristics and immune activity were analyzed. The polysaccharide was a homogeneous macromolecular polysaccharide with smooth flat flakes surface structure and molecular weight of 2.34 × 10
Identifiants
pubmed: 36332314
pii: S0045-2068(22)00620-4
doi: 10.1016/j.bioorg.2022.106214
pii:
doi:
Substances chimiques
Polysaccharides
0
Immunologic Factors
0
Cytokines
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
106214Informations de copyright
Copyright © 2022. Published by Elsevier Inc.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.