Two neuronal peptides encoded from a single transcript regulate mitochondrial complex III in
CRISPR/Cas9
D. melanogaster
genetics
genomics
mitochondria
neurodegeneration
neuroscience
paralogs
peptide
smORF
Journal
eLife
ISSN: 2050-084X
Titre abrégé: Elife
Pays: England
ID NLM: 101579614
Informations de publication
Date de publication:
08 11 2022
08 11 2022
Historique:
received:
15
08
2022
accepted:
01
11
2022
pubmed:
9
11
2022
medline:
24
11
2022
entrez:
8
11
2022
Statut:
epublish
Résumé
Naturally produced peptides (<100 amino acids) are important regulators of physiology, development, and metabolism. Recent studies have predicted that thousands of peptides may be translated from transcripts containing small open-reading frames (smORFs). Here, we describe two peptides in
Identifiants
pubmed: 36346220
doi: 10.7554/eLife.82709
pii: 82709
pmc: PMC9681215
doi:
pii:
Substances chimiques
Electron Transport Complex III
EC 7.1.1.8
Peptides
0
Banques de données
Dryad
['10.5061/dryad.83bk3j9vc']
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Howard Hughes Medical Institute
Pays : United States
Organisme : NHGRI NIH HHS
ID : R01 HG009352
Pays : United States
Organisme : NIH HHS
ID : R24 OD019847
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM067761
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM007748
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM084947
Pays : United States
Déclaration de conflit d'intérêts
JB, BU, IP, JR, FE, ZZ, BB, SC, DS, NP No competing interests declared, HB Reviewing editor, eLife
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