Spatial genomics maps the structure, nature and evolution of cancer clones.

Female Humans Breast Neoplasms / genetics Carcinoma, Intraductal, Noninfiltrating / genetics Clonal Evolution / genetics Clone Cells / metabolism Genomics Mutation Tumor Microenvironment / genetics Whole Genome Sequencing Transcriptome Reproducibility of Results Microdissection Algorithms

Journal

Nature

ISSN: 1476-4687

Titre abrégé: Nature

Pays: England

ID NLM: 0410462

Informations de publication

Date de publication:
Nov 2022

Historique:

received: 21 04 2021

accepted: 07 10 2022

pubmed: 10 11 2022

medline: 22 11 2022

entrez: 9 11 2022

Statut: ppublish

Résumé

Genome sequencing of cancers often reveals mosaics of different subclones present in the same tumour

Identifiants

DOI: 10.1038/s41586-022-05425-2 PMID: 36352222 PMC: PMC9668746

pubmed: 36352222

doi: 10.1038/s41586-022-05425-2

pii: 10.1038/s41586-022-05425-2

pmc: PMC9668746

doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

Pagination

594-602

Subventions

Organisme : NCI NIH HHS

ID : U54 CA225088

Pays : United States

Organisme : NCI NIH HHS

ID : P50 CA168504

Pays : United States

Organisme : Wellcome Trust

ID : 108413/A/15/D

Pays : United Kingdom

Organisme : Wellcome Trust

ID : 214584/Z/18/Z

Pays : United Kingdom

Commentaires et corrections

Type : CommentIn

Informations de copyright

Références

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