Propolis Efficacy: The Quest for Eco-Friendly Solvents.

Propolis / pharmacology Solvents Antioxidants / pharmacology Microbial Sensitivity Tests Methicillin-Resistant Staphylococcus aureus Candida albicans Ethanol / chemistry Escherichia coli Anti-Infective Agents / pharmacology Water
antibacterial activity antioxidant potential phenolic compounds propolis propolis extraction propolis extraction solvents

Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
03 Nov 2022
Historique:
received: 07 10 2022
revised: 01 11 2022
accepted: 01 11 2022
entrez: 11 11 2022
pubmed: 12 11 2022
medline: 15 11 2022
Statut: epublish

Résumé

Propolis, a natural product made by bees with resins and balsams, is known for its complex chemical composition and remarkable bioactivities. In this study, propolis extraction was studied seeking extracts with strong bioactivities using less orthodox solvents, with some derived from apiary products. For that, a propolis sample collected from Gerês apiary in 2018 (G18) was extracted by maceration with six different solvents: absolute ethanol, ethanol/water (7:3), honey brandy, mead, propylene glycol and water. The solvent influence on the chemical composition and antioxidant and antimicrobial activities of the extracts was investigated. Antioxidant potential was assessed by the DPPH free-radical-scavenging assay and the antimicrobial activity by the agar dilution method. Chemical composition of the extracts was determined in vitro by three colorimetric assays: total ortho-diphenols, phenolics and flavonoids contents and the LC-MS technique. To our knowledge, this is the first time that solvents such as honey brandy and mead have been studied. Honey brandy showed considerable potential to extract propolis active compounds able to inhibit the growth of bacteria such as the methicillin-sensitive

Identifiants

DOI: 10.3390/molecules27217531 PMID: 36364353 PMC: PMC9655633
pubmed: 36364353
pii: molecules27217531
doi: 10.3390/molecules27217531
pmc: PMC9655633
pii:
doi:

Substances chimiques

Propolis 9009-62-5
Solvents 0
Antioxidants 0
Ethanol 3K9958V90M
Anti-Infective Agents 0
Water 059QF0KO0R

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Fundação para a Ciência e Tecnologia
ID : PD/BD/128276/2017
Organisme : Fundação para a Ciência e Tecnologia
ID : PD/00122/2012
Organisme : Fundação para a Ciência e Tecnologia
ID : CITAB research unit (UIDB/04033/2020), CBMA research unit (Contrato-Programa UIDB/04050/2020), Centre of Chemistry (UID/QUI/0686/2016)

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Auteurs

Ana Sofia Freitas (AS)

CITAB-Centre for the Research and Technology of Agro-Environmental and Biological Sciences, University of Minho, 4710-057 Braga, Portugal.
Department of Biology, School of Sciences, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.
CBMA-Centre of Molecular and Environmental Biology, University of Minho, 4710-057 Braga, Portugal.

Ana Cunha (A)

Department of Biology, School of Sciences, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.
CBMA-Centre of Molecular and Environmental Biology, University of Minho, 4710-057 Braga, Portugal.
ORCID: 0000-0003-0822-8248

Pier Parpot (P)

CQUM-Chemistry Center of the University of Minho, Department of Chemistry, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.
CEB-Centre of Biological Engineering, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.

Susana M Cardoso (SM)

LAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.
ORCID: 0000-0002-7882-737X

Rui Oliveira (R)

Department of Biology, School of Sciences, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.
CBMA-Centre of Molecular and Environmental Biology, University of Minho, 4710-057 Braga, Portugal.
ORCID: 0000-0002-3989-8925

Cristina Almeida-Aguiar (C)

Department of Biology, School of Sciences, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.
CBMA-Centre of Molecular and Environmental Biology, University of Minho, 4710-057 Braga, Portugal.
ORCID: 0000-0001-8223-8634

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Classifications MeSH

questionsmedicales.fr › Mélanges complexes › Produits biologiques › Exsudats végétaux › Résines végétales › Propolis › Propolis Efficacy: The Quest for Eco-Friendly Solvents.
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Solvants › Propolis Efficacy: The Quest for Eco-Friendly Solvents.
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Agents protecteurs › Antioxydants › Propolis Efficacy: The Quest for Eco-Friendly Solvents.
questionsmedicales.fr › Techniques d'investigation › Évaluation préclinique de médicament › Tests de sensibilité microbienne › Propolis Efficacy: The Quest for Eco-Friendly Solvents.
questionsmedicales.fr › Bactéries › Bactéries à Gram positif › Cocci à Gram positif › Staphylococcaceae › Staphylococcus › Staphylococcus aureus › Staphylococcus aureus résistant à la méticilline › Propolis Efficacy: The Quest for Eco-Friendly Solvents.
questionsmedicales.fr › Eucaryotes › Champignons › Levures › Candida › Candida albicans › Propolis Efficacy: The Quest for Eco-Friendly Solvents.
questionsmedicales.fr › Composés chimiques organiques › Alcools › Éthanol › Propolis Efficacy: The Quest for Eco-Friendly Solvents.
questionsmedicales.fr › Bactéries › Proteobacteria › Gammaproteobacteria › Enterobacteriaceae › Escherichia › Escherichia coli › Propolis Efficacy: The Quest for Eco-Friendly Solvents.
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Propolis Efficacy: The Quest for Eco-Friendly Solvents.
questionsmedicales.fr › Produits chimiques inorganiques › Composés de l'oxygène › Oxydes › Eau › Propolis Efficacy: The Quest for Eco-Friendly Solvents.