Anxiety in Wiedemann-Steiner syndrome.
KMT2A
anxiety
developmental psychopathology
genetics/genetic disorders
mental health
Journal
American journal of medical genetics. Part A
ISSN: 1552-4833
Titre abrégé: Am J Med Genet A
Pays: United States
ID NLM: 101235741
Informations de publication
Date de publication:
02 2023
02 2023
Historique:
revised:
22
10
2022
received:
12
07
2022
accepted:
27
10
2022
pmc-release:
01
02
2024
pubmed:
15
11
2022
medline:
13
1
2023
entrez:
14
11
2022
Statut:
ppublish
Résumé
This study examined anxiety in Wiedemann-Steiner syndrome (WSS). Eighteen caregivers and participants with WSS completed the parent- and self-report versions of the Screen for Child Anxiety Related Disorder or the adapted version of the Screen for Adult Anxiety Related Disorder. Approximately 33.33% of parents and 65% of participants with WSS rated in the clinical range for overall anxiety. Across anxiety subtypes, parents primarily indicated concerns with Separation Anxiety (72%), which was also endorsed by the majority of participants with WSS (82%). The emergent trend showed Total Anxiety increased with age based on parent-informant ratings. The behavioral phenotype of WSS includes elevated anxiety. Clinical management should include incorporating early behavioral interventions to bolster emotion regulation given the observed risk of anxiety with age.
Identifiants
pubmed: 36373844
doi: 10.1002/ajmg.a.63040
pmc: PMC9907226
mid: NIHMS1855586
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
437-444Subventions
Organisme : NICHD NIH HHS
ID : P50 HD103538
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR003098
Pays : United States
Organisme : NICHD NIH HHS
ID : K08 HD086250
Pays : United States
Informations de copyright
© 2022 Wiley Periodicals LLC.
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