MPS1 localizes to end-on microtubule-attached kinetochores to promote microtubule release.

Microtubules
Aurora B MPS1 PP2A-B56 cell division chromosome kinase kinetochore mitosis phosphatase spindle assembly checkpoint

Journal

Current biology : CB
ISSN: 1879-0445
Titre abrégé: Curr Biol
Pays: England
ID NLM: 9107782

Informations de publication

Date de publication:
05 12 2022
Historique:
received: 25 05 2022
revised: 07 09 2022
accepted: 20 10 2022
pubmed: 18 11 2022
medline: 15 12 2022
entrez: 17 11 2022
Statut: ppublish

Résumé

In eukaryotes, the spindle assembly checkpoint protects genome stability in mitosis by preventing chromosome segregation until incorrect microtubule-kinetochore attachment geometries have been eliminated and chromosome biorientation has been completed. These error correction and checkpoint processes are linked by the conserved Aurora B and MPS1 Ser/Thr kinases.

Identifiants

DOI: 10.1016/j.cub.2022.10.047 PMID: 36395767
pubmed: 36395767
pii: S0960-9822(22)01695-5
doi: 10.1016/j.cub.2022.10.047
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

5200-5208.e8

Subventions

Organisme : Medical Research Council
ID : MR/K006703/1
Pays : United Kingdom

Informations de copyright

Copyright © 2022 The Author(s). Published by Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests The authors declare no competing interests.

Auteurs

Daniel Hayward (D)

Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, Oxfordshire OX1 3RE, UK.

Emile Roberts (E)

Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, Oxfordshire OX1 3RE, UK.

Ulrike Gruneberg (U)

Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, Oxfordshire OX1 3RE, UK. Electronic address: ulrike.gruneberg@path.ox.ac.uk.

Articles similaires

Regulation of minimal spindle midzone organization by mitotic kinases.

Wei Ming Lim, Wei-Xiang Chew, Arianna Esposito Verza et al.
1.00
Spindle Apparatus Phosphorylation Humans CDC2 Protein Kinase Protein Serine-Threonine Kinases

Kinetochore dynein is sufficient to biorient chromosomes and remodel the outer kinetochore.

Bram Prevo, Dhanya K Cheerambathur, William C Earnshaw et al.
1.00
Kinetochores Caenorhabditis elegans Animals Caenorhabditis elegans Proteins Microtubules

Live-cell imaging under centrifugation characterized the cellular force for nuclear centration in the

Makoto Goda, Michael Shribak, Zenki Ikeda et al.
1.00
Animals Caenorhabditis elegans Cell Nucleus Embryo, Nonmammalian Microtubules

BEACH domain-containing protein SPIRRIG facilitates microtubule cytoskeleton-associated trichome morphogenesis in Arabidopsis.

Linyu Niu, Wenjuan Xie, Qian Li et al.
1.00
Arabidopsis Trichomes Microtubules Arabidopsis Proteins Morphogenesis

Classifications MeSH

questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Cytosquelette › Microtubules › MPS1 localizes to end-on microtubule-attached...