Stereotactic Radiotherapy in the Management of Ventricular Tachycardias: More Questions than Answers?

Humans Radiosurgery Tachycardia, Ventricular / radiotherapy Catheter Ablation Heart Diseases / surgery
Catheter ablation Stereotactic arrhythmia radiotherapy Stereotactic body radiotherapy Ventricular tachycardia

Journal

Cardiac electrophysiology clinics
ISSN: 1877-9190
Titre abrégé: Card Electrophysiol Clin
Pays: United States
ID NLM: 101549998

Informations de publication

Date de publication:
12 2022
Historique:
entrez: 17 11 2022
pubmed: 18 11 2022
medline: 22 11 2022
Statut: ppublish

Résumé

Stereotactic body radiotherapy is a recent promising therapeutic alternative in cases of failed catheter ablation for recurrent ventricular tachycardias (VTs) in patients with structural heart disease. Initial clinical experience with a single radiation dose of 25 Gy shows reasonable efficacy in the reduction of VT recurrences with acceptable acute toxicity. Many unanswered questions remain, including unknown mechanism of action, variable time to effect, optimal method of substrate targeting, long-term safety, and definition of an optimal candidate for this treatment."

Identifiants

DOI: 10.1016/j.ccep.2022.06.010 PMID: 36396193
pubmed: 36396193
pii: S1877-9182(22)00059-4
doi: 10.1016/j.ccep.2022.06.010
pii:
doi:

Types de publication

Journal Article Review Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

779-792

Informations de copyright

Copyright © 2022 Elsevier Inc. All rights reserved.

Auteurs

Jana Haskova (J)

Department of Cardiology, IKEM, Vídeňská 1958/9, Prague 140 21, Czech Republic. Electronic address: hasj@ikem.cz.

Marek Sramko (M)

Department of Cardiology, IKEM, Vídeňská 1958/9, Prague 140 21, Czech Republic.

Jakub Cvek (J)

Department of Oncology, University Hospital Ostrava and Ostrava University Medical School, 17 listopadu 1790/5, Ostrava-Poruba 708 00 Czech Republic.

Josef Kautzner (J)

Department of Cardiology, IKEM, Vídeňská 1958/9, Prague 140 21, Czech Republic; Palacky University Medical School, Olomouc, Czech Republic.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Stereotactic Radiotherapy in the Management of...
questionsmedicales.fr › Techniques d'investigation › Techniques stéréotaxiques › Radiochirurgie › Stereotactic Radiotherapy in the Management of...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Troubles du rythme cardiaque › Tachycardie › Tachycardie ventriculaire › Stereotactic Radiotherapy in the Management of...
questionsmedicales.fr › Procédures de chirurgie opératoire › Techniques d'ablation › Ablation par radiofréquence › Ablation par cathéter › Stereotactic Radiotherapy in the Management of...
questionsmedicales.fr › Maladies cardiovasculaires › Cardiopathies › Stereotactic Radiotherapy in the Management of...