Risk Factors for Postoperative Complications After Surgical Treatment of Type B and C Injuries of the Thoracolumbar Spine.


Journal

World neurosurgery
ISSN: 1878-8769
Titre abrégé: World Neurosurg
Pays: United States
ID NLM: 101528275

Informations de publication

Date de publication:
Feb 2023
Historique:
received: 08 11 2022
accepted: 13 11 2022
pubmed: 20 11 2022
medline: 16 2 2023
entrez: 19 11 2022
Statut: ppublish

Résumé

Unstable thoracolumbar spinal injuries benefit from surgical fixation. However, perioperative complications significantly affect outcomes in surgicallytreated spine patients. We evaluated associations between risk factors and postoperative complications in patients surgically treated for thoracolumbar spine fractures. We conducted a retrospective multicenter study collating data from 21 spine centers across 9 countries on the treatment of AOSpine types B and C injuries of the thoracolumbar spine treated via a posterior approach. Comparative analysis was performed between patients with postoperative complications and those without. Univariate and multivariable analyses were performed. Among 535 patients, at least 1 complication occurred in 43%. The most common surgical complication was surgical-site infection (6.9%), while the most common medical complication was urinary tract infection (13.8%). Among 136 patients with American Spinal Injury Association (ASIA) Impairment Scalelevel A disability, 77.9% experienced at least 1 complication. The rate of complications also rose sharply among patients waiting >3 days for surgery (P<0.001), peaking at 68.4% among patients waiting ≥30 days. On multivariable analysis, significant predictors of complications were surgery at a governmental hospital (odds ratio = 3.38, 95% confidence interval = 1.73-6.60), having ≥1 comorbid illness (2.44, 1.61-3.70), surgery delayed due to health instability (2.56, 1.50-4.37), and ASIA Impairment Scalelevel A (3.36, 1.78-6.35), while absence of impairment (0.39, 0.22-0.71), ASIAlevel E (0.39, 0.22-0.67) and, unexpectedly, delay caused by operating room unavailability (0.60, 0.36-0.99) were protective. Types B and C thoracolumbar spine injuries are associated with a high risk of postoperative complications, especially common at governmental hospitals, and among patients with comorbidity, health instability, longer delays to surgery, and worse preoperative neurologic status.

Sections du résumé

BACKGROUND BACKGROUND
Unstable thoracolumbar spinal injuries benefit from surgical fixation. However, perioperative complications significantly affect outcomes in surgicallytreated spine patients. We evaluated associations between risk factors and postoperative complications in patients surgically treated for thoracolumbar spine fractures.
METHODS METHODS
We conducted a retrospective multicenter study collating data from 21 spine centers across 9 countries on the treatment of AOSpine types B and C injuries of the thoracolumbar spine treated via a posterior approach. Comparative analysis was performed between patients with postoperative complications and those without. Univariate and multivariable analyses were performed.
RESULTS RESULTS
Among 535 patients, at least 1 complication occurred in 43%. The most common surgical complication was surgical-site infection (6.9%), while the most common medical complication was urinary tract infection (13.8%). Among 136 patients with American Spinal Injury Association (ASIA) Impairment Scalelevel A disability, 77.9% experienced at least 1 complication. The rate of complications also rose sharply among patients waiting >3 days for surgery (P<0.001), peaking at 68.4% among patients waiting ≥30 days. On multivariable analysis, significant predictors of complications were surgery at a governmental hospital (odds ratio = 3.38, 95% confidence interval = 1.73-6.60), having ≥1 comorbid illness (2.44, 1.61-3.70), surgery delayed due to health instability (2.56, 1.50-4.37), and ASIA Impairment Scalelevel A (3.36, 1.78-6.35), while absence of impairment (0.39, 0.22-0.71), ASIAlevel E (0.39, 0.22-0.67) and, unexpectedly, delay caused by operating room unavailability (0.60, 0.36-0.99) were protective.
CONCLUSIONS CONCLUSIONS
Types B and C thoracolumbar spine injuries are associated with a high risk of postoperative complications, especially common at governmental hospitals, and among patients with comorbidity, health instability, longer delays to surgery, and worse preoperative neurologic status.

Identifiants

pubmed: 36402303
pii: S1878-8750(22)01612-6
doi: 10.1016/j.wneu.2022.11.059
pii:
doi:

Types de publication

Multicenter Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e520-e528

Investigateurs

Carlos Zanardi (C)
Nelson Picard (N)
Maximiliano Donato (M)
Alberto Gorgas (A)
Efrén Peña (E)
Óscar González (Ó)
Sergio Mandiola (S)
Rodrigo Remondino (R)
Pablo Nicolas Ortiz (PN)
José Jiménez (J)
Jose de Jesus Gonzalez (J)
Oscar Martinez (O)
Pedro Reyes (P)
Juan Jara (J)
Julio Burgos (J)
Martin Gagliardi (M)
Alejandro Morales Ciancio (AM)
Daniel Uruchi (D)
Ricardo Martínez (R)
Nicolás Mireles (N)
Paulo Henrique Meira (PH)
Nelson Astur (N)
Robert Meves (R)
Rian Vieira (R)
Renan Borges (R)
Jennyfer Chaves (J)
Ricardo Guimaraes (R)
Matheus Balen (M)
Juan J Zamorano (JJ)
Guilherme Rocha Zanini (GR)
Germano Senna (G)
Paulo Roberto Cabrera (PR)
Fausto Ordoñez (F)
FranlyArismendy Vásquez (F)
Jefferson Daniel (J)
Jose Carlos Veiga (JC)
Pedro Del Santoro (PD)
Andre Luis Sebben (AL)
Vinicius Orso (V)
Ricardo Penteado (R)
Christian Pino (C)
Esther Velarde (E)
Charbel Jacob (C)
Wanderson Dias (W)
Jose Ignacio Ujhelly (JI)
Ayelen Estay (A)
Gustavo Noleto (G)
Icaro de Sousa (I)
Robson Amorim (R)
Marlon Carneiro (M)
Fabián Montoya (F)
David Flórez (D)
Raphael Augusto Corrêa (RA)
Bastianon Santiago (B)
Alvaro Silva Gonzalez (AS)

Informations de copyright

Copyright © 2022 Elsevier Inc. All rights reserved.

Auteurs

Juan P Cabrera (JP)

Department of Neurosurgery, Hospital Clínico Regional de Concepción, and Faculty of Medicine, University of Concepción, Concepción, Chile. Electronic address: jucabrera@udec.cl.

Charles A Carazzo (CA)

Neurosurgery, University of Passo Fundo, São Vicente de Paulo Hospital, Passo Fundo, RS, Brazil.

Alfredo Guiroy (A)

Spine Unit, Orthopedic Department, Hospital Español de Mendoza, Mendoza, Argentina.

Kevin P White (KP)

Science Right Research Consulting, London, Ontario, Canada.

Joana Guasque (J)

Hospital Universitario Cajuru, Curitiba, Brazil.

Ericson Sfreddo (E)

Department of Neurosurgery, Hospital Cristo Redentor, Porto Alegre, Brazil.

Andrei F Joaquim (AF)

Department of Neurosurgery, University of Campinas (UNICAMP), Campinas-SP, Brazil.

Ratko Yurac (R)

Department of Orthopedic and Traumatology, University del Desarrollo, and Spine Unit, Department of Traumatology, Clínica Alemana, Santiago, Chile.

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