Antibiotic prescription after tooth extraction in adults: a retrospective cohort study in Austria.
Antibiotic prophylaxis
Cohort studies
Dentistry
Endocarditis prevention & control
Journal
BMC oral health
ISSN: 1472-6831
Titre abrégé: BMC Oral Health
Pays: England
ID NLM: 101088684
Informations de publication
Date de publication:
20 11 2022
20 11 2022
Historique:
received:
26
07
2022
accepted:
03
11
2022
entrez:
20
11
2022
pubmed:
21
11
2022
medline:
23
11
2022
Statut:
epublish
Résumé
Broad spectrum antibiotics are often used for the prophylaxis of infectious endocarditis and treatment of odontogenic infections, but there are limited data related to antibiotic use and adherence to prescription guidelines. METHODS: Data from patients with tooth extraction between 2014 and 2018 were selected from a database of a regional health insurance fund. We created three data sets, one based on all tooth extractions, one on multiple teeth extractions, and one including only single tooth extraction. After data collection, descriptive analysis was carried out. The differences in prescription pattern of antibiotic medicine were tested by χ From 43,863 patients with tooth extraction, 53% were female, and 3,983 patients (9.1%) filled a prescription for antibiotic medicine. From 43,863 patients, 157 patients (0.4%) had endocarditis risk, but only 8 patients of these (5.1%) filled an antibiotic prescription. In total, 9,234 patients had multiple and 34,437 patients had only one tooth extraction. Patients with more than one tooth extraction received more often antibiotic treatment (10.7%) compared to those with single tooth extractions (χ In this retrospective cohort study, dentists did not discriminate prophylactic antibiotic prescription with regard to endocarditis risk status. A factor influencing prescribing behaviour of antibiotic medicines was the number of extracted teeth.
Sections du résumé
BACKGROUND
Broad spectrum antibiotics are often used for the prophylaxis of infectious endocarditis and treatment of odontogenic infections, but there are limited data related to antibiotic use and adherence to prescription guidelines. METHODS: Data from patients with tooth extraction between 2014 and 2018 were selected from a database of a regional health insurance fund. We created three data sets, one based on all tooth extractions, one on multiple teeth extractions, and one including only single tooth extraction. After data collection, descriptive analysis was carried out. The differences in prescription pattern of antibiotic medicine were tested by χ
RESULTS
From 43,863 patients with tooth extraction, 53% were female, and 3,983 patients (9.1%) filled a prescription for antibiotic medicine. From 43,863 patients, 157 patients (0.4%) had endocarditis risk, but only 8 patients of these (5.1%) filled an antibiotic prescription. In total, 9,234 patients had multiple and 34,437 patients had only one tooth extraction. Patients with more than one tooth extraction received more often antibiotic treatment (10.7%) compared to those with single tooth extractions (χ
CONCLUSIONS
In this retrospective cohort study, dentists did not discriminate prophylactic antibiotic prescription with regard to endocarditis risk status. A factor influencing prescribing behaviour of antibiotic medicines was the number of extracted teeth.
Identifiants
pubmed: 36404324
doi: 10.1186/s12903-022-02556-w
pii: 10.1186/s12903-022-02556-w
pmc: PMC9677908
doi:
Substances chimiques
Anti-Bacterial Agents
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
519Informations de copyright
© 2022. The Author(s).
Références
Aust Dent J. 2000 Sep;45(3):179-86; quiz 214
pubmed: 11062935
J Oral Maxillofac Surg. 2014 Oct;72(10):1938-56
pubmed: 25234529
J Clin Periodontol. 2017 Mar;44 Suppl 18:S135-S144
pubmed: 28266112
Br J Oral Maxillofac Surg. 2001 Apr;39(2):134-7
pubmed: 11286448
Eur J Oral Sci. 2017 Aug;125(4):280-287
pubmed: 28653438
Int J Oral Maxillofac Surg. 2019 Feb;48(2):263-273
pubmed: 30145064
J Clin Exp Dent. 2017 Jan 1;9(1):e141-e149
pubmed: 28149479
Circulation. 2008 Jun 17;117(24):3118-25
pubmed: 18541739
Medicina (Kaunas). 2018 Dec 01;54(6):
pubmed: 30513764
Acta Odontol Scand. 2020 Oct;78(7):529-534
pubmed: 32293215
Eur Heart J. 2015 Nov 21;36(44):3075-3128
pubmed: 26320109
Int J Environ Res Public Health. 2020 Apr 09;17(7):
pubmed: 32283707
Circulation. 2017 Jun 20;135(25):e1159-e1195
pubmed: 28298458
J Craniofac Surg. 2011 Mar;22(2):551-3
pubmed: 21403575
J Neurointerv Surg. 2015 Aug;7(8):619-22
pubmed: 24951285
Swiss Dent J. 2014;124(3):294-302
pubmed: 24671748
Biomed Res Int. 2021 Jul 16;2021:5599724
pubmed: 34327231
J Craniomaxillofac Surg. 2015 Jul;43(6):847-54
pubmed: 25958767
J Am Dent Assoc. 2017 Dec;148(12):878-886.e1
pubmed: 28941554
Cochrane Database Syst Rev. 2021 Feb 24;2:CD003811
pubmed: 33624847
Lancet. 2022 Feb 12;399(10325):629-655
pubmed: 35065702
J Am Dent Assoc. 2008 Jan;139 Suppl:3S-24S
pubmed: 18167394
Euro Surveill. 2019 Nov;24(46):
pubmed: 31771707
Clin Infect Dis. 1993 Aug;17(2):188-94
pubmed: 8399865
J Korean Assoc Oral Maxillofac Surg. 2020 Feb;46(1):49-57
pubmed: 32158681
Br Dent J. 2016 May 27;220(10):499
pubmed: 27228911
J Nat Sci Biol Med. 2017 Jul-Dec;8(2):229-234
pubmed: 28781493
J Am Dent Assoc. 2017 Mar;148(3):172-178.e1
pubmed: 28126225
J Clin Periodontol. 2015 Oct;42(10):922-32
pubmed: 26362756
J Antimicrob Chemother. 2004 Apr;53(4):567-76
pubmed: 14985274
J Craniomaxillofac Surg. 2017 Nov;45(11):1854-1859
pubmed: 28939205
BMC Geriatr. 2021 Feb 10;21(1):117
pubmed: 33568102
Eur Heart J. 2009 Oct;30(19):2369-413
pubmed: 19713420
J Am Coll Cardiol. 2022 Sep 13;80(11):1029-1041
pubmed: 35987887
J Oral Maxillofac Surg. 2013 Jun;71(6):994-9
pubmed: 23434159
Int Dent J. 2014 Jun;64(3):138-43
pubmed: 24410046
Molecules. 2022 Mar 21;27(6):
pubmed: 35335369
Community Dent Oral Epidemiol. 2016 Apr;44(2):145-53
pubmed: 26507098
Med Oral Patol Oral Cir Bucal. 2006 Mar 01;11(2):E188-205
pubmed: 16505802
J Antimicrob Chemother. 2019 Jul 1;74(7):2075-2082
pubmed: 31225607
Euro Surveill. 2016 Nov 17;21(46):
pubmed: 27918266
Ther Clin Risk Manag. 2010 Jul 21;6:301-6
pubmed: 20668712
PLoS One. 2021 May 14;16(5):e0251400
pubmed: 33989309
Oral Surg Oral Med Oral Pathol Oral Radiol. 2016 Oct;122(4):403-25
pubmed: 27499028
Int J Technol Assess Health Care. 2012 Apr;28(2):171-9
pubmed: 22559761
Eur Heart J. 2022 Feb 12;43(7):561-632
pubmed: 34453165
Int Endod J. 2009 Dec;42(12):1112-7
pubmed: 19912383
PLoS One. 2018 Apr 25;13(4):e0196419
pubmed: 29694412
J Investig Clin Dent. 2017 Nov;8(4):
pubmed: 27778471