Neostriatum neuronal TRPV

Animals Rats Receptors, GABA-A / metabolism Rats, Wistar Substantia Nigra Bicuculline / pharmacology GABA-A Receptor Antagonists / pharmacology Neural Pathways / physiology
Anandamide Caudate nucleus Deep layers of superior colliculus Endovanilloid receptors Striatonigral-nigrotectal GABAergic pathways Unconditioned fear

Journal

Brain research bulletin
ISSN: 1873-2747
Titre abrégé: Brain Res Bull
Pays: United States
ID NLM: 7605818

Informations de publication

Date de publication:
Jan 2023
Historique:
received: 30 05 2022
revised: 14 11 2022
accepted: 17 11 2022
pubmed: 23 11 2022
medline: 15 12 2022
entrez: 22 11 2022
Statut: ppublish

Résumé

Several lines of evidence have demonstrated that the cannabinoid type 1 receptor (CB Fluorescent neural tract tracers were deposited in either CPu or in SNpr. Wistar rats received injection of vehicle, anandamide (AEA), either at low (50 pmol) or high (100 pmol) concentrations in CPu followed by bicuculline microinjections in dlSC. Connections between CPu, the SNpr and dlSC were demonstrated. The GABA These findings suggest that while pre-synaptic CB1-signalling subserves an indirect facilitatory effect of AEA on striato-nigral pathways causing panicolytic-like responses through midbrain tectum enhanced activity, post-synaptic TRPV

Identifiants

DOI: 10.1016/j.brainresbull.2022.11.014 PMID: 36414159
pubmed: 36414159
pii: S0361-9230(22)00322-7
doi: 10.1016/j.brainresbull.2022.11.014
pii:
doi:

Substances chimiques

Receptors, GABA-A 0
Bicuculline Y37615DVKC
anandamide UR5G69TJKH
GABA-A Receptor Antagonists 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

128-141

Informations de copyright

Copyright © 2022 The Authors. Published by Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that there are no conflicts of interest concerning the presented work.

Auteurs

Juliana Almeida da Silva (JA)

Ribeirão Preto Medical School of the University of São Paulo (FMRP-USP), Department of Pharmacology, Laboratory of Neuroanatomy and Neuropsychobiology, Ribeirão Preto, São Paulo, Brazil; Behavioural Neuroscience Institute (INeC), Ribeirão Preto, São Paulo, Brazil. Electronic address: ju.silva@usp.br.

Rafael Carvalho Almada (RC)

Ribeirão Preto Medical School of the University of São Paulo (FMRP-USP), Department of Pharmacology, Laboratory of Neuroanatomy and Neuropsychobiology, Ribeirão Preto, São Paulo, Brazil; São Paulo State University (UNESP), School of Science and Literature, Department of Biological Sciences, Assis, São Paulo, Brazil; Behavioural Neuroscience Institute (INeC), Ribeirão Preto, São Paulo, Brazil.

Luiz Luciano Falconi-Sobrinho (LL)

Ribeirão Preto Medical School of the University of São Paulo (FMRP-USP), Department of Pharmacology, Laboratory of Neuroanatomy and Neuropsychobiology, Ribeirão Preto, São Paulo, Brazil; Behavioural Neuroscience Institute (INeC), Ribeirão Preto, São Paulo, Brazil.

Glauce Regina Pigatto (GR)

Ribeirão Preto Medical School of the University of São Paulo (FMRP-USP), Department of Pharmacology, Laboratory of Neuroanatomy and Neuropsychobiology, Ribeirão Preto, São Paulo, Brazil; Behavioural Neuroscience Institute (INeC), Ribeirão Preto, São Paulo, Brazil.

Paloma Molina Hernandes (PM)

Ribeirão Preto Medical School of the University of São Paulo (FMRP-USP), Department of Pharmacology, Laboratory of Neuroanatomy and Neuropsychobiology, Ribeirão Preto, São Paulo, Brazil; São Paulo State University (UNESP), School of Science and Literature, Department of Biological Sciences, Assis, São Paulo, Brazil.

Norberto Cysne Coimbra (NC)

Ribeirão Preto Medical School of the University of São Paulo (FMRP-USP), Department of Pharmacology, Laboratory of Neuroanatomy and Neuropsychobiology, Ribeirão Preto, São Paulo, Brazil; Behavioural Neuroscience Institute (INeC), Ribeirão Preto, São Paulo, Brazil; NAP-USP-Neurobiology of Emotions Research Centre (NuPNE), Ribeirão Preto Medical School of the University of São Paulo, Ribeirão Preto, São Paulo, Brazil. Electronic address: nccoimbr@fmrp.usp.br.

Articles similaires

Evaluating the efficacy of telesurgery with dual console SSI Mantra Surgical Robotic System: experiment on animal model and clinical trials.

Sudhir Prem Srivastava, Vishwajyoti Pascual Srivastava, Avinesh Singh et al.
1.00
Robotic Surgical Procedures Animals Humans Telemedicine Models, Animal

Odour generalisation and detection dog training.

Lyn Caldicott, Thomas W Pike, Helen E Zulch et al.
1.00
Animals Odorants Dogs Generalization, Psychological Smell

FBXO22 inhibits colitis and colorectal carcinogenesis by regulating the degradation of the S2448-phosphorylated form of mTOR.

Minle Li, Xuan Chen, Pengfei Qu et al.
1.00
Animals TOR Serine-Threonine Kinases Colorectal Neoplasms Colitis Mice

Use of organic material provided by an automatic enrichment device by weaner pigs and its influence on tail lesions.

Philipp Heseker, Jeanette Probst, Stefanie Ammer et al.
1.00
Animals Tail Swine Behavior, Animal Animal Husbandry

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Neostriatum neuronal TRPV
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Neostriatum neuronal TRPV
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs aux neuromédiateurs › Récepteurs aux acides aminés › Récepteurs GABA › Récepteurs GABA-A › Neostriatum neuronal TRPV
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Rat Wistar › Neostriatum neuronal TRPV
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Tronc cérébral › Mésencéphale › Pédoncule cérébral › Substantia nigra › Neostriatum neuronal TRPV
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Isoquinoléines › Benzylisoquinoléines › Bicuculline › Neostriatum neuronal TRPV
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Agents neuromédiateurs › Agents GABA › Antagonistes GABA › Antagonistes du récepteur GABA-A › Neostriatum neuronal TRPV
questionsmedicales.fr › Système nerveux › Voies nerveuses › Neostriatum neuronal TRPV