Graph theoretical analysis reveals the functional role of the left ventral occipito-temporal cortex in speech processing.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
21 11 2022
21 11 2022
Historique:
received:
30
06
2022
accepted:
09
11
2022
entrez:
22
11
2022
pubmed:
23
11
2022
medline:
25
11
2022
Statut:
epublish
Résumé
The left ventral occipito-temporal cortex (left-vOT) plays a key role in reading. Interestingly, the area also responds to speech input, suggesting that it may have other functions beyond written word recognition. Here, we adopt graph theoretical analysis to investigate the left-vOT's functional role in the whole-brain network while participants process spoken sentences in different contexts. Overall, different connectivity measures indicate that the left-vOT acts as an interface enabling the communication between distributed brain regions and sub-networks. During simple speech perception, the left-vOT is systematically part of the visual network and contributes to the communication between neighboring areas, remote areas, and sub-networks, by acting as a local bridge, a global bridge, and a connector, respectively. However, when speech comprehension is explicitly required, the specific functional role of the area and the sub-network to which the left-vOT belongs change and vary with the quality of speech signal and task difficulty. These connectivity patterns provide insightful information on the contribution of the left-vOT in various contexts of language processing beyond its role in reading. They advance our general understanding of the neural mechanisms underlying the flexibility of the language network that adjusts itself according to the processing context.
Identifiants
pubmed: 36414688
doi: 10.1038/s41598-022-24056-1
pii: 10.1038/s41598-022-24056-1
pmc: PMC9681757
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
20028Subventions
Organisme : Agence Nationale de la Recherche
ID : ANR-19-CE28-0001-01
Organisme : Agence Nationale de la Recherche
ID : ANR-13-JSH2-0002
Organisme : Agence Nationale de la Recherche
ID : ANR-11-LABX- 0036 (BLRI)
Organisme : Agence Nationale de la Recherche
ID : ANR-13-JSH2-0002
Organisme : Agence Nationale de la Recherche, France
ID : ANR-16-CONV-0002 (ILCB)
Organisme : Agence Nationale de la Recherche, France
ID : ANR-11- INBS-0006
Informations de copyright
© 2022. The Author(s).
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