Prognosis in asymptomatic patients with discordantly graded aortic valve stenosis based on pressure recovery adjusted valve area.
Aortic Valve Stenosis
Echocardiography
Hypertension
Journal
Open heart
ISSN: 2053-3624
Titre abrégé: Open Heart
Pays: England
ID NLM: 101631219
Informations de publication
Date de publication:
11 2022
11 2022
Historique:
received:
12
10
2022
accepted:
14
11
2022
entrez:
25
11
2022
pubmed:
26
11
2022
medline:
30
11
2022
Statut:
ppublish
Résumé
We hypothesised that patients with asymptomatic aortic stenosis (AS) who remain with discordantly graded aortic valve stenosis (DGAS) after adjustment for pressure recovery in the aortic root represents a subgroup of patients with increased cardiovascular risk. Data from 1353 patients with asymptomatic mild-moderate AS and preserved left ventricular ejection fraction enrolled in the Simvastatin and Ezetimibe in AS study was used. DGAS was identified as combined pressure adjusted valve area (energy loss) <1.0 cm² and mean aortic gradient<40 mm Hg (DGAS DGAS Patients with asymptomatic AS who remain with discordant grading after adjustment for pressure recovery have increased risk for HF and death. NCT00092677.
Identifiants
pubmed: 36428084
pii: openhrt-2022-002159
doi: 10.1136/openhrt-2022-002159
pmc: PMC9703352
pii:
doi:
Banques de données
ClinicalTrials.gov
['NCT00092677']
Types de publication
Clinical Trial
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
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