A single-cell analysis framework allows for characterization of CSF leukocytes and their tissue of origin in multiple sclerosis.

Humans Multiple Sclerosis Single-Cell Analysis Leukocytes Central Nervous System Multiple Sclerosis, Relapsing-Remitting

Journal

Science translational medicine
ISSN: 1946-6242
Titre abrégé: Sci Transl Med
Pays: United States
ID NLM: 101505086

Informations de publication

Date de publication:
30 11 2022
Historique:
entrez: 30 11 2022
pubmed: 1 12 2022
medline: 3 12 2022
Statut: ppublish

Résumé

Peripheral central nervous system (CNS)-infiltrating lymphocytes are a hallmark of relapsing-remitting multiple sclerosis. Tissue-resident memory T cells (T

Identifiants

DOI: 10.1126/scitranslmed.adc9778 PMID: 36449599
pubmed: 36449599
doi: 10.1126/scitranslmed.adc9778
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

eadc9778

Auteurs

Patrick Ostkamp (P)

Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Münster 48149, Germany.
ORCID: 0000-0002-2634-4173

Marie Deffner (M)

Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Münster 48149, Germany.

Andreas Schulte-Mecklenbeck (A)

Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Münster 48149, Germany.
ORCID: 0000-0003-3855-4706

Christian Wünsch (C)

Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Münster 48149, Germany.
ORCID: 0000-0003-4367-3857

I-Na Lu (IN)

Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Münster 48149, Germany.

Gregory F Wu (GF)

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.
ORCID: 0000-0003-3588-0637

Susan Goelz (S)

Oregon Health and Science University, Portland, OR 97239, USA.

Philip L De Jager (PL)

Center for Translational and Computational Neuroimmunology and Multiple Sclerosis Center, Department of Neurology, Columbia University Irving Medical Center, New York, NY 10032, USA.
ORCID: 0000-0002-8057-2505

Tanja Kuhlmann (T)

Institute of Neuropathology, University Hospital Münster, Münster 48149, Germany.

Catharina C Gross (CC)

Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Münster 48149, Germany.
ORCID: 0000-0002-4872-9189

Luisa Klotz (L)

Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Münster 48149, Germany.
ORCID: 0000-0001-5439-9633

Gerd Meyer Zu Hörste (G)

Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Münster 48149, Germany.
ORCID: 0000-0002-4341-4719

Heinz Wiendl (H)

Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Münster 48149, Germany.

Tilman Schneider-Hohendorf (T)

Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Münster 48149, Germany.
ORCID: 0000-0002-3717-5176

Nicholas Schwab (N)

Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Münster 48149, Germany.
ORCID: 0000-0001-5494-9885

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › A single-cell analysis framework allows for...
questionsmedicales.fr › Maladies du système immunitaire › Maladies auto-immunes › Maladies auto-immunes du système nerveux › Maladies démyélinisantes auto-immunes du SNC › Sclérose en plaques › A single-cell analysis framework allows for...
questionsmedicales.fr › Techniques d'investigation › Techniques cytologiques › Analyse sur cellule unique › A single-cell analysis framework allows for...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › A single-cell analysis framework allows for...
questionsmedicales.fr › Système nerveux › Système nerveux central › A single-cell analysis framework allows for...
questionsmedicales.fr › Maladies du système immunitaire › Maladies auto-immunes › Maladies auto-immunes du système nerveux › Maladies démyélinisantes auto-immunes du SNC › Sclérose en plaques › Sclérose en plaques récurrente-rémittente › A single-cell analysis framework allows for...