Effect of xylazine sedation on testicular blood flow, testicular echotexture, and circulating hormones in Shiba goats.
Color Doppler ultrasonography
Goats
Hormones
Testicular hemodynamics
Xylazine
Journal
Veterinary research communications
ISSN: 1573-7446
Titre abrégé: Vet Res Commun
Pays: Switzerland
ID NLM: 8100520
Informations de publication
Date de publication:
Jun 2023
Jun 2023
Historique:
received:
03
09
2022
accepted:
23
11
2022
medline:
26
5
2023
pubmed:
2
12
2022
entrez:
1
12
2022
Statut:
ppublish
Résumé
Under field conditions, sedation may be required for a full assessment of the reproductive potential of farm animals. The present study aimed to investigate the effect of xylazine sedation on testicular hemodynamics (TBF), echotexture, testicular volume (TV), and circulating hormones in goats. Sixteen male Shiba goats were sedated using the recommended dose of xylazine (0.05 mg/Kg BW). Testicular hemodynamics were evaluated using color-pulsed Doppler ultrasonography before and after sedation. Echotexture of the testicular parenchyma and TV were assessed using computerized image analysis. Concentrations of testosterone, estradiol (E2), inhibin, cortisol, follicle-stimulating hormone (FSH), and luteinizing hormone (LH) were measured using radioimmunoassay. There were no effects of xylazine sedation in TBF, TV, testicular parenchyma parameters, and concentrations of testosterone, inhibin, FSH, and LH (P ˃ 0.05). However, after sedation, there was significantly (P ˂ 0.05) lower cortisol and E2 concentration (42.88 ± 6.79 ng/ml and 2.47 ± 0.58 pg/ml, respectively) than before sedation (94.89 ± 13.74 ng/ml and 8.65 ± 1.79 pg/ml, respectively). The required time to perform the full scanning of the testis was significantly lower (8.50 ± 0.38 min) after xylazine sedation compared to the non-sedated goats (25.75 ± 1.14 min). In conclusion, xylazine sedation may be practically recommended for the evaluation of TBF in goats because it did not significantly alter velocities parameters and Doppler indices of blood flow within the testicular arteries. Most plasma hormones did not significantly change; however, E2 and cortisol were significantly reduced after xylazine administration.
Identifiants
pubmed: 36454511
doi: 10.1007/s11259-022-10046-1
pii: 10.1007/s11259-022-10046-1
doi:
Substances chimiques
Xylazine
2KFG9TP5V8
Hydrocortisone
WI4X0X7BPJ
Luteinizing Hormone
9002-67-9
Follicle Stimulating Hormone
9002-68-0
Testosterone
3XMK78S47O
Inhibins
57285-09-3
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
849-859Subventions
Organisme : Japan Society for the Promotion of Science
ID : FY19 Standard-ID No. P19101
Informations de copyright
© 2022. The Author(s), under exclusive licence to Springer Nature B.V.
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