Management of comatose survivors of out-of-hospital cardiac arrest in Europe: current treatment practice and adherence to guidelines. A joint survey by the Association for Acute CardioVascular Care (ACVC) of the ESC, the European Resuscitation Council (ERC), the European Society for Emergency Medicine (EUSEM), and the European Society of Intensive Care Medicine (ESICM).


Journal

European heart journal. Acute cardiovascular care
ISSN: 2048-8734
Titre abrégé: Eur Heart J Acute Cardiovasc Care
Pays: England
ID NLM: 101591369

Informations de publication

Date de publication:
09 Feb 2023
Historique:
received: 26 06 2022
revised: 15 10 2022
accepted: 30 11 2022
pubmed: 2 12 2022
medline: 14 2 2023
entrez: 1 12 2022
Statut: ppublish

Résumé

International guidelines give recommendations for the management of comatose out-of-hospital cardiac arrest (OHCA) survivors. We aimed to investigate adherence to guidelines and disparities in the treatment of OHCA in hospitals in Europe. A web-based, multi-institutional, multinational survey in Europe was conducted using an electronic platform with a predefined questionnaire developed by experts in post-resuscitation care. The survey was disseminated to all members of the societies via email, social media, websites, and newsletters in June 2021. Of 252 answers received, 237 responses from different units were included and 166 (70%) were from cardiac arrest centres. First-line vasopressor used was noradrenaline in 195 (83%) and the first-line inotrope was dobutamine in 148 (64%) of the responses. Echocardiography is available 24/7 in 204 (87%) institutions. Targeted temperature management was used in 160 (75%) institutions for adult comatose survivors of OHCA with an initial shockable rhythm. Invasive or external cooling methods with feedback were used in 72 cardiac arrest centres (44%) and 17 (24%) non-cardiac arrest centres (P < 0.0003). A target temperature between 32 and 34°C was preferred by 46 centres (21%); a target between 34 and 36°C by 103 centres (52%); and <37.5°C by 35 (16%). Multimodal neuroprognostication was poorly implemented and a follow-up at 3 months after discharge was done in 71 (30%) institutions. Post-resuscitation care is not well established and varies among centres in European hospitals. Cardiac arrest centres have a higher coherence with guidelines compared with respondents from non-cardiac arrest centres. The overall inconsistency in approaches and deviation from recommendations could be a focus for improvement.

Identifiants

pubmed: 36454812
pii: 6862066
doi: 10.1093/ehjacc/zuac153
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

96-105

Commentaires et corrections

Type : ErratumIn

Informations de copyright

© The Author(s) 2022. Published by Oxford University Press on behalf of the European Society of Cardiology. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Déclaration de conflit d'intérêts

Conflict of interest: None declared.

Auteurs

Pablo Jorge-Perez (P)

Department of Cardiology, Canary Islands University Hospital, La Laguna, 38320 Santa Cruz de Tenerife, Spain.

Nikolaos Nikolaou (N)

Intensive Cardiac Care Unit, Cardiology Department, Konstantopouleio General Hospital, Athens, Greece.

Katia Donadello (K)

Department of Anesthesia and Intensive Care B, Department of Surgery, Dentistry, Gynaecology and Paediatrics, University of Verona, AOUI-University Hospital Integrated Trust of Verona, Policlinico G.B. Rossi, P.le L. Scuro, Verone, Italy.

Abdo Khoury (A)

Department of Emergency Medicine and Critical Care, Besançon University Hospital, Besançon, France.
INSERM CIC 1431, Besançon University Hospital, Besançon, France.

Wilhelm Behringer (W)

Department of Emergency Medicine, Medical University Vienna, Vienna, Austria.

Christian Hassager (C)

Department of Cardiology, University Hospital of Copenhagen, Rigshospitalet, The Heart Center, Copenhagen, Denmark.

Bernd Boettiger (B)

Medical Faculty and University Hospital, University of Cologne, Cologne, Germany.
European Resuscitation Council (ERC), Niel, Belgium.
German Resuscitation Council (GRC), Ulm, Germany.

Alessandro Sionis (A)

Intensive Cardiac Care Unit, Cardiology Department, Hospital de Sant Pau, IIB-Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.
Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBER-CV), Madrid, Spain.

Jerry Nolan (J)

Warwick Medical School, University of Warwick, Coventry, UK.
Department of Anaesthesia and Intensive Care Medicine, Royal United Hospital, Bath, UK.

Alain Combes (A)

Sorbonne Université INSERM Unité Mixte de Recherche (UMRS) 1166, Institute of Cardiometabolism and Nutrition, Paris, France.
Service de Médecine Intensive-Réanimation, Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Sorbonne Université, INSERM, UMRS_1166-ICAN, Institute of Cardiometabolism and Nutrition, Paris, France.

Tom Quinn (T)

Kingston University and St. Georges, University of London, London, UK.

Susanna Price (S)

Departments of Cardiology and Critical Care, Royal Brompton & Harefield Hospitals, London, UK.
National Heart and Lung Institute, Imperial College London, London, UK.

Johannes Grand (J)

Department of Cardiology, Amager-Hvidovre Hospital, University Hospital of Copenhagen, Copenhagen, Denmark.

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