Disruption of the HLA-E/NKG2X axis is associated with uncontrolled HIV infections.

Humans HIV Infections Viremia Epitopes Cytokines HLA-E Antigens
HIV HLA-E NKG2A NKG2C Natural Killer cells

Journal

Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960

Informations de publication

Date de publication:
2022
Historique:
received: 25 08 2022
accepted: 18 10 2022
entrez: 5 12 2022
pubmed: 6 12 2022
medline: 7 12 2022
Statut: epublish

Résumé

The contribution of the HLA-E/NKG2X axis in NK-mediated control of HIV infection remains unclear. We have studied the relationship between HLA-E expression and phenotypical as well as functional characteristics of NK cells, in the context of chronic HIV infection and in an

Identifiants

DOI: 10.3389/fimmu.2022.1027855 PMID: 36466823 PMC: PMC9716355
pubmed: 36466823
doi: 10.3389/fimmu.2022.1027855
pmc: PMC9716355
doi:

Substances chimiques

Epitopes 0
Cytokines 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

1027855

Subventions

Organisme : NIAID NIH HHS
ID : P01 AI131568
Pays : United States
Organisme : NIAID NIH HHS
ID : P01 AI178375
Pays : United States

Informations de copyright

Copyright © 2022 Romero-Martín, Duran-Castells, Olivella, Rosás-Umbert, Ruiz-Riol, Sanchez, Hartigan-O´Connor, Mothe, Olvera and Brander.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Références

Front Cell Infect Microbiol. 2020 Mar 25;10:102
pubmed: 32269968
Gut. 2018 Nov;67(11):2035-2044
pubmed: 28899983
J Biol Chem. 2013 Mar 22;288(12):8679-8690
pubmed: 23335510
Nat Commun. 2019 Aug 29;10(1):3897
pubmed: 31467285
J Immunol Methods. 2016 Jul;434:16-23
pubmed: 27084117
Front Immunol. 2019 May 28;10:1179
pubmed: 31231370
Eur J Immunol. 2004 Aug;34(8):2313-21
pubmed: 15259029
Eur J Immunol. 2018 Feb;48(2):293-305
pubmed: 29124751
J Virol. 2005 Oct;79(19):12365-74
pubmed: 16160163
J Immunol. 2002 Aug 15;169(4):1948-58
pubmed: 12165520
AIDS Res Hum Retroviruses. 2008 Jan;24(1):72-82
pubmed: 18275350
Front Immunol. 2017 Sep 20;8:1176
pubmed: 28979268
J Virol. 2017 Jul 27;91(16):
pubmed: 28592538
Immunotherapy. 2019 Aug;11(11):931-935
pubmed: 31218904
Nat Rev Microbiol. 2014 Nov;12(11):750-64
pubmed: 25402363
Hum Immunol. 1997 Jan;52(1):33-40
pubmed: 9021407
Antivir Ther. 2005;10(1):95-107
pubmed: 15751767
Front Immunol. 2018 Apr 20;9:686
pubmed: 29731749
PLoS One. 2017 Jan 11;12(1):e0167640
pubmed: 28076376
Immunol Lett. 2018 Oct;202:65-72
pubmed: 30172717
Immunity. 1996 Jun;4(6):565-71
pubmed: 8673703
Hum Immunol. 2000 Nov;61(11):1059-65
pubmed: 11137208
Mol Immunol. 2020 Apr;120:101-112
pubmed: 32113130
PLoS Pathog. 2016 Feb 01;12(2):e1005421
pubmed: 26828202
Int J Immunopathol Pharmacol. 2005 Apr-Jun;18(2):269-76
pubmed: 15888249
Stem Cells. 2014 Apr;32(4):1021-31
pubmed: 24307574
J Immunol. 2000 May 15;164(10):5019-22
pubmed: 10799855
Oncotarget. 2016 Nov 8;7(45):72961-72977
pubmed: 27662664
Nat Immunol. 2002 Nov;3(11):1006-12
pubmed: 12407408
Curr Opin Immunol. 2008 Feb;20(1):30-8
pubmed: 18206359
Clin Infect Dis. 2015 Oct 1;61(7):1169-78
pubmed: 26063721
Science. 2016 Feb 12;351(6274):714-20
pubmed: 26797147
Nat Immunol. 2018 Jul;19(7):723-732
pubmed: 29915296
Proc Natl Acad Sci U S A. 2008 May 6;105(18):6696-701
pubmed: 18448674
Immunity. 2017 Nov 21;47(5):820-833
pubmed: 29166586
EMBO J. 1999 Aug 2;18(15):4250-60
pubmed: 10428963
Nat Med. 2003 Jul;9(7):928-35
pubmed: 12819779
Bone Marrow Transplant. 2009 May;43(9):693-9
pubmed: 19011664
J Immunol Methods. 1992 Jan 21;146(1):91-103
pubmed: 1735786
Front Immunol. 2016 Aug 29;7:323
pubmed: 27621731
J Immunol Res. 2014;2014:938561
pubmed: 24741633
Immunity. 2015 Mar 17;42(3):443-56
pubmed: 25786176
J Virol. 2019 Sep 30;93(20):
pubmed: 31375574
Clin Exp Immunol. 2019 May;196(2):167-177
pubmed: 30968409
J Immunol. 1998 May 1;160(9):4375-85
pubmed: 9574542
Blood. 2010 Nov 11;116(19):3865-74
pubmed: 20733159
Trends Immunol. 2007 Jun;28(6):252-9
pubmed: 17466596
Immunol Res. 2006;35(3):263-78
pubmed: 17172651
Blood. 2001 May 15;97(10):3146-51
pubmed: 11342442
J Biol Chem. 2003 Feb 14;278(7):5082-90
pubmed: 12411439
Nat Commun. 2017 Jun 06;8:15776
pubmed: 28585539
Immunogenetics. 2016 Jan;68(1):29-41
pubmed: 26552660
Nat Commun. 2018 Mar 23;9(1):1212
pubmed: 29572470
J Exp Med. 1998 Mar 2;187(5):813-8
pubmed: 9480992
J Immunol Res. 2016;2016:2695396
pubmed: 27699181
Cancer Immunol Res. 2014 May;2(5):410-22
pubmed: 24795354
J Clin Invest. 2019 Jun 18;129(9):3770-3785
pubmed: 31211698
Eur J Immunol. 2003 Sep;33(9):2410-8
pubmed: 12938217
Nat Immunol. 2008 May;9(5):503-10
pubmed: 18425107
AIDS. 2010 Jan 2;24(1):27-34
pubmed: 19910789
Mol Ther. 2015 Aug;23(8):1358-1367
pubmed: 26050990

Auteurs

Luis Romero-Martín (L)

IrsiCaixa AIDS Research Institute, Hospital Germans Trias i Pujol, Institute for Health Science Research Germans Trias i Pujol (IGTP), Badalona, Spain.
Universitat Autonoma de Barcelona (UAB), Barcelona, Spain.

Clara Duran-Castells (C)

IrsiCaixa AIDS Research Institute, Hospital Germans Trias i Pujol, Institute for Health Science Research Germans Trias i Pujol (IGTP), Badalona, Spain.
Universitat Autonoma de Barcelona (UAB), Barcelona, Spain.

Mireia Olivella (M)

University of Vic-Central University of Catalonia (UVic-UCC), Vic, Spain.

Míriam Rosás-Umbert (M)

IrsiCaixa AIDS Research Institute, Hospital Germans Trias i Pujol, Institute for Health Science Research Germans Trias i Pujol (IGTP), Badalona, Spain.

Marta Ruiz-Riol (M)

IrsiCaixa AIDS Research Institute, Hospital Germans Trias i Pujol, Institute for Health Science Research Germans Trias i Pujol (IGTP), Badalona, Spain.
CIBERINFEC, Centro de Investigación Biomédica en Red, Instituto de Salud Carlos III, Madrid, Spain.

Jorge Sanchez (J)

Impacta, Lima, Peru.

Dennis Hartigan-O Connor (D)

California National Primate Research Center and Department of Medical Microbiology and Immunology, University of California, Davis, Davis, CA, United States.
Division of Experimental Medicine, Department of Medicine, University of California, San Francisco, San Francisco, CA, United States.

Beatriz Mothe (B)

IrsiCaixa AIDS Research Institute, Hospital Germans Trias i Pujol, Institute for Health Science Research Germans Trias i Pujol (IGTP), Badalona, Spain.
University of Vic-Central University of Catalonia (UVic-UCC), Vic, Spain.
Fundació Lluita contra la Sida, Infectious Disease Department, Hospital Universitari Germans Trias i Pujol, Badalona, Spain.

Àlex Olvera (À)

IrsiCaixa AIDS Research Institute, Hospital Germans Trias i Pujol, Institute for Health Science Research Germans Trias i Pujol (IGTP), Badalona, Spain.
University of Vic-Central University of Catalonia (UVic-UCC), Vic, Spain.
CIBERINFEC, Centro de Investigación Biomédica en Red, Instituto de Salud Carlos III, Madrid, Spain.

Christian Brander (C)

IrsiCaixa AIDS Research Institute, Hospital Germans Trias i Pujol, Institute for Health Science Research Germans Trias i Pujol (IGTP), Badalona, Spain.
University of Vic-Central University of Catalonia (UVic-UCC), Vic, Spain.
CIBERINFEC, Centro de Investigación Biomédica en Red, Instituto de Salud Carlos III, Madrid, Spain.
ICREA, Barcelona, Spain.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Disruption of the HLA-E/NKG2X axis is...
questionsmedicales.fr › Maladies du système immunitaire › Déficits immunitaires › Infections à VIH › Disruption of the HLA-E/NKG2X axis is...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Inflammation › Sepsie › Virémie › Disruption of the HLA-E/NKG2X axis is...
questionsmedicales.fr › Facteurs biologiques › Antigènes › Épitopes › Disruption of the HLA-E/NKG2X axis is...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Disruption of the HLA-E/NKG2X axis is...