Classifying the Large Vestibular Aqueduct: Morphometry to Audiometry.
Journal
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
ISSN: 1537-4505
Titre abrégé: Otol Neurotol
Pays: United States
ID NLM: 100961504
Informations de publication
Date de publication:
01 01 2023
01 01 2023
Historique:
entrez:
12
12
2022
pubmed:
13
12
2022
medline:
15
12
2022
Statut:
ppublish
Résumé
Large vestibular aqueduct (LVA) is the most common inner ear dysplasia identified in patients with hearing loss. Our objective was to systematically quantify LVA morphologies and correlate imaging findings with established audiometric outcomes. Retrospective review. Tertiary referral center. Patients with large vestibular aqueduct identified radiographically, with or without hearing loss. Diagnostic only. Vestibular aqueduct (VA) width at midpoint, width at external aperture, and length were measured on cross-sectional imaging. Morphology was classified as type I (borderline), type II (tubular), or type III (funneled). Audiometric endpoints included air/bone conduction, pure tone averages, and air-bone gaps at 250 and 500 Hz. Statistical associations were evaluated using linear regression models, adjusted for age at first audiogram and sex. One hundred seventeen patients (197 ears) were included, with mean age at first audiogram of 22.2 years (standard deviation, 21.7 yr). Imaging features associated with poor audiometric outcomes were increasing VA width at midpoint and external aperture, decreasing VA length, dilated extraosseous endolymphatic sac, cochleovestibular malformations, and increasing VA type (III > II > I). Quantitative LVA measurements and a standardized morphologic classification system aid in prediction of early audiometric endpoints.
Identifiants
pubmed: 36509439
doi: 10.1097/MAO.0000000000003748
pii: 00129492-202301000-00013
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
47-53Informations de copyright
Copyright © 2022, Otology & Neurotology, Inc.
Déclaration de conflit d'intérêts
C.L.W.D. and M.L.C. are consultants for Advanced Bionics Corp., Cochlear Corp., and MED-EL GmbH. The remaining authors disclose no conflicts of interest.
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