Effectiveness of a training intervention in increasing the use of misoprostol in postabortion care in Malawi: a quasi-experimental study.


Journal

BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874

Informations de publication

Date de publication:
14 12 2022
Historique:
entrez: 14 12 2022
pubmed: 15 12 2022
medline: 17 12 2022
Statut: epublish

Résumé

The study was conducted to determine effectiveness of a training intervention in increasing use of misoprostol in management of incomplete abortions. A quasi-experimental study with training intervention on use of misoprostol in treatment of incomplete abortion. Five secondary-level public hospitals in Malawi, one in urban and four in semiurban settings. Three intervention and two control sites. Records of women treated for first-trimester incomplete abortion from March to May 2020 (baseline) and April to June 2021 (endline). Clinical data were collected from 865 records, 421 before and 444 after the intervention in all study sites. Three-hour theoretical training sessions for 81 healthcare workers were conducted in July 2020 at the three intervention sites. Proportion of women with incomplete abortion treated with misoprostol before and after the intervention. The proportion of women treated with sharp curettage at the study sites. At the intervention sites, there was a significant increase in use of misoprostol from 22.8% (95% CI 17.9% to 28.0%) to 35.9% (95% CI 30.5% to 41.6%) and significant reduction in use of sharp curettage from 48.1% (95% CI 41.9% to 54.3%) to 39.4% (95% CI 35.3% to 42.6%) p<0.01 at baseline and endline, respectively. The use of misoprostol was significantly higher at the intervention sites with OR of 5.02 (95% CI 1.7 to 14.7) p<0.05 compared with control sites at the endline in multivariable models, and there was a difference in the difference of 14.4% ((95% CI 10.4% to 18.2%) p<0.001) between the intervention and control sites after the intervention. A training intervention effectively increased the use of misoprostol in the treatment of incomplete abortions. Increasing misoprostol use will make treatment of incomplete abortion cheaper, easier and more easily accessible. Making quality postabortion care accessible to more women may reduce maternal morbidity and mortality. Further training interventions are recommended.

Identifiants

pubmed: 36517095
pii: bmjopen-2022-061886
doi: 10.1136/bmjopen-2022-061886
pmc: PMC9756167
doi:

Substances chimiques

Misoprostol 0E43V0BB57
Abortifacient Agents, Nonsteroidal 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e061886

Informations de copyright

© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Références

Health Policy Plan. 2017 Apr 1;32(3):305-313
pubmed: 27616307
BMJ Glob Health. 2018 Sep 23;3(5):e000823
pubmed: 30271625
Lancet. 2006 Nov 25;368(9550):1908-19
pubmed: 17126724
Int J Gynaecol Obstet. 2014 Jul;126 Suppl 1:S24-7
pubmed: 24800657
BMC Health Serv Res. 2015 Dec 17;15:562
pubmed: 26677840
Int J Environ Res Public Health. 2018 Feb 21;15(2):
pubmed: 29466308
Int J Gynaecol Obstet. 2011 Jan;112(1):40-4
pubmed: 21122848
Lancet. 2015 Jun 13;385(9985):2392-8
pubmed: 25817472
Glob Health Action. 2013 Apr 24;6:1-11
pubmed: 23618341
BMC Pregnancy Childbirth. 2012 Nov 14;12:127
pubmed: 23150927
Int J Gynaecol Obstet. 2014 Jul;126 Suppl 1:S28-30
pubmed: 24786140
BMC Health Serv Res. 2014 Jan 21;14:28
pubmed: 24447321
Reprod Health Matters. 2015 Feb;22(44 Suppl 1):16-25
pubmed: 25702065
BMJ Glob Health. 2018 Jun 29;3(3):e000692
pubmed: 29989078
PLoS One. 2014 Jun 25;9(6):e100728
pubmed: 24963882
Afr J Reprod Health. 2011 Dec;15(4):42-50
pubmed: 22571104
Int J Gynaecol Obstet. 2011 Nov;115(2):121-6
pubmed: 21885049
Int Perspect Sex Reprod Health. 2013 Jun;39(2):88-96
pubmed: 23895885
Acta Obstet Gynecol Scand. 2002 Nov;81(11):1060-5
pubmed: 12421175

Auteurs

Bertha Magreta Chakhame (B)

School of Maternal, Neonatal and Reproductive Health, Kamuzu University of Health Sciences, Blantyre, Malawi.
Department of Public Health and Nursing, The Norwegian University of Science and Technology, Trondheim, Norway.

Elisabeth Darj (E)

Department of Public Health and Nursing, The Norwegian University of Science and Technology, Trondheim, Norway.

Mphatso Mwapasa (M)

Department of Public Health and Nursing, The Norwegian University of Science and Technology, Trondheim, Norway.

Ursula Kafulafula (U)

School of Maternal, Neonatal and Reproductive Health, Kamuzu University of Health Sciences, Blantyre, Malawi.

Grace Chiudzu (G)

Department of Obstetrics and Gynecology, Kamuzu Central Hospital, Lilongwe, Malawi.

Alfred Maluwa (A)

Department of Research and Postgraduate Outreach, Malawi University of Science and Technology, Thyolo, Malawi.

Address Malata (A)

Department of Research and Postgraduate Outreach, Malawi University of Science and Technology, Thyolo, Malawi.

Jon Øyvind Odland (JØ)

Department of Public Health and Nursing, The Norwegian University of Science and Technology, Trondheim, Norway.
Faculty of Biosciences and Aquaculture, Nord University, Bodø, Norway.
Department of Public Health, University of Pretoria, Pretoria, South Africa.

Maria Lisa Odland (ML)

Department of Public Health and Nursing, The Norwegian University of Science and Technology, Trondheim, Norway maria.l.odland@ntnu.no.
Institute of Applied Health Research, University of Birmingham, Birmingham, UK.
Department of Obstetrics and Gynaecology, St. Olav's Hospital, Trondheim, Norway.
Malawi-Liverpool-Wellcome Trust Research Institute, Blantyre, Malawi.
Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, UK.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH