Cysteine-Selective Modification of Peptides and Proteins via Desulfurative C-C Bond Formation.
bioconjugation
cysteine
desulfurization
post-translational modifications
site-selective
Journal
Chemistry (Weinheim an der Bergstrasse, Germany)
ISSN: 1521-3765
Titre abrégé: Chemistry
Pays: Germany
ID NLM: 9513783
Informations de publication
Date de publication:
16 Mar 2023
16 Mar 2023
Historique:
received:
11
08
2022
pubmed:
20
12
2022
medline:
22
3
2023
entrez:
19
12
2022
Statut:
ppublish
Résumé
The site-selective modification of peptides and proteins facilitates the preparation of targeted therapeutic agents and tools to interrogate biochemical pathways. Among the numerous bioconjugation techniques developed to install groups of interest, those that generate C(sp
Identifiants
pubmed: 36534955
doi: 10.1002/chem.202202503
doi:
Substances chimiques
Cysteine
K848JZ4886
Proteins
0
Peptides
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e202202503Subventions
Organisme : Wellcome Trust
ID : 202250/Z/16/Z
Pays : United Kingdom
Informations de copyright
© 2022 The Authors. Chemistry - A European Journal published by Wiley-VCH GmbH.
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