Indications, preferences, global practice patterns and outcomes in retrograde intrarenal surgery (RIRS) for renal stones in adults: results from a multicenter database of 6669 patients of the global FLEXible ureteroscopy Outcomes Registry (FLEXOR).


Journal

World journal of urology
ISSN: 1433-8726
Titre abrégé: World J Urol
Pays: Germany
ID NLM: 8307716

Informations de publication

Date de publication:
Feb 2023
Historique:
received: 08 09 2022
accepted: 09 12 2022
pubmed: 20 12 2022
medline: 25 2 2023
entrez: 19 12 2022
Statut: ppublish

Résumé

To collect a multicentric database on behalf of TOWER research group to assess practice patterns and outcomes of retrograde intrarenal surgery (RIRS) for kidney stones. Inclusion criteria: age ≥ 18 years, normal renal/calyceal system anatomy, calculi of any size, number, and position. January 2018 and August 2021. Stone-free status: absence of fragments > 2 mm, assessed post procedure according to the local protocol (KUB X-Ray and/or ultrasound or non-contrast CT scan). Twenty centers from fifteen countries enrolled 6669 patients. There were 4407 (66.2%) men. Mean age was 49.3 ± 15.59 years. Pain was the most frequent symptom indication for intervention (62.6%). 679 (10.2%) patients underwent RIRS for an incidental finding of stones. 2732 (41.0%) patients had multiple stones. Mean stone size was 10.04 ± 6.84 mm. A reusable flexible ureteroscope was used in 4803 (72.0%) procedures. A sheath-less RIRS was performed in 454 (6.8%) cases. Holmium:YAG laser was used in 4878 (73.1%) cases. A combination of dusting and fragmentation was the most common lithotripsy mode performed (64.3%). Mean operation time was 62.40 ± 17.76 min. 119 (1.8%) patients had an intraoperative injury of the ureter due to UAS insertion. Mean postoperative stay was 3.62 ± 3.47 days. At least one postoperative complication occurred in 535 (8.0%) patients. Sepsis requiring intensive care admission occurred in 84 (1.3%) patients. Residual fragments were detected in 1445 (21.7%) patients. Among the latter, 744 (51.5%) patients required a further intervention. Our database contributes real-world data to support to a better understanding of modern RIRS practice and outcomes.

Identifiants

pubmed: 36536170
doi: 10.1007/s00345-022-04257-z
pii: 10.1007/s00345-022-04257-z
doi:

Types de publication

Multicenter Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

567-574

Commentaires et corrections

Type : CommentIn

Informations de copyright

© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Références

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Auteurs

Vineet Gauhar (V)

Department of Urology, Ng Teng Fong General Hospital, Singapore, Singapore.

Ben Hall Chew (BH)

Department of Urology, University of British Columbia, Vancouver, Canada.

Olivier Traxer (O)

Department of Urology AP-HP, Sorbonne University, Tenon Hospital, Paris, France.

Thomas Tailly (T)

Department of Urology, University Hospital of Ghent, Ghent, Belgium.

Esteban Emiliani (E)

Urology Department, Universidad Autónoma de Barcelona, Fundación PuigvertBarcelona, Spain.

Takaaki Inoue (T)

Department of Urology and Stone Center, Hara Genitourinary Hospital, Kobe City, Hyogo, Japan.

Heng Chin Tiong (HC)

Department of Urology, Ng Teng Fong General Hospital, Singapore, Singapore.

Chu Ann Chai (CA)

Urology Unit, Department of Surgery, University Malaya, Kuala Lumpur, Malaysia.

Mohamed Amine Lakmichi (MA)

Department of Urology, University Hospital Mohammed the VIth of Marrakesh, Marrakesh, Morocco.

Yiloren Tanidir (Y)

Department of Urology, Marmara University School of Medicine, Istanbul, Turkey.

Saeed Bin Hamri (S)

Division of Urology, Department of Surgery, Ministry of the National Guard Health Affairs, King Saud Bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.

Devang Desai (D)

Department of Urology, Toowoomba Hospital, University of Queensland, Brisbane, Australia.

Sarvajit Biligere (S)

Department of Urology, Ng Teng Fong General Hospital, Singapore, Singapore.

Anil Shrestha (A)

Department of Urology, National Academy of Medical Sciences, Bir Hospital, Kathmandu, Nepal.

Boyke Soebhali (B)

Medical Faculty, Mulawarman University, Abdul Wahab Sjahranie Hospital, Samarinda, Indonesia.

William Ong Lay Keat (WOL)

Department of Urology, Penang General Hospital, Penang, Malaysia.

Vaddi Chandra Mohan (VC)

Department of Urology, Preeti Urology and Kidney Hospital, Hyderabad, Telangana, India.

Tanuj Paul Bhatia (TP)

Department of Urology, Sarvodaya Healthcare, Faridabad, Haryana, India.

Abhishek Singh (A)

Department of Urology, Muljibhai Patel Urological Hospital, Nadiad, Gujarat, India.

Mohamed Saleem (M)

Department of Urology, Apis Kidney Stone Institute, Urology Research and Day Care Center, Mangalore, Karnataka, India.

Dmitry Gorelov (D)

Endourology Department, Saint-Petersburg State Medical University, Saint-Petersburg, Russia.

Nariman Gadzhiev (N)

Endourology Department, Saint-Petersburg State Medical University, Saint-Petersburg, Russia.

Amelia Pietropaolo (A)

Department of Urology, University Hospitals Southampton, NHS Trust, Southampton, UK.

Andrea Benedetto Galosi (AB)

Urology Unit, Azienda Ospedaliero-Universitaria Ospedali Riuniti Di Ancona, Università Politecnica Delle Marche, Via Conca 71, 60126, Ancona, Italy.

Deepak Ragoori (D)

Department of Urology, Asian Institute of Nephrology & Urology, Irram Manzil Colony, Hyderabad, Telangana, India.

Jeremy Yuen-Chun Teoh (JY)

S. H. Ho Urology Centre, Department of Surgery, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.

Bhaskar Kumar Somani (BK)

Department of Urology, University Hospitals Southampton, NHS Trust, Southampton, UK.

Daniele Castellani (D)

Urology Unit, Azienda Ospedaliero-Universitaria Ospedali Riuniti Di Ancona, Università Politecnica Delle Marche, Via Conca 71, 60126, Ancona, Italy. castellanidaniele@gmail.com.

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