A Multi-Trait Gaussian Kernel Genomic Prediction Model under Three Tunning Strategies.

Bayesian optimization genomic selection grid search kernels multi-trait

Journal

Genes
ISSN: 2073-4425
Titre abrégé: Genes (Basel)
Pays: Switzerland
ID NLM: 101551097

Informations de publication

Date de publication:
03 12 2022
Historique:
received: 02 11 2022
revised: 27 11 2022
accepted: 01 12 2022
entrez: 23 12 2022
pubmed: 24 12 2022
medline: 27 12 2022
Statut: epublish

Résumé

While genomic selection (GS) began revolutionizing plant breeding when it was proposed around 20 years ago, its practical implementation is still challenging as many factors affect its accuracy. One such factor is the choice of the statistical machine learning method. For this reason, we explore the tuning process under a multi-trait framework using the Gaussian kernel with a multi-trait Bayesian Best Linear Unbiased Predictor (GBLUP) model. We explored three methods of tuning (manual, grid search and Bayesian optimization) using 5 real datasets of breeding programs. We found that using grid search and Bayesian optimization improve between 1.9 and 6.8% the prediction accuracy regarding of using manual tuning. While the improvement in prediction accuracy in some cases can be marginal, it is very important to carry out the tuning process carefully to improve the accuracy of the GS methodology, even though this entails greater computational resources.

Identifiants

pubmed: 36553548
pii: genes13122279
doi: 10.3390/genes13122279
pmc: PMC9778253
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Bill & Melinda Gates Foundation
ID : INV-003439
Pays : United States

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Auteurs

Statistics Study Program, Universitas Negeri Yogyakarta, Yogyakarta 55281, Indonesia.

Abelardo Montesinos-López (A)

Centro Universitario de Ciencias Exactas e Ingenierías (CUCEI), Universidad de Guadalajara, Guadalajara 44430, Jalisco, Mexico.

Bernabe Cano-Páez (B)

Facultad de Ciencias, Universidad Nacional Autónoma de México (UNAM), México City 04510, Mexico.

J Cricelio Montesinos-López (JC)

Department of Public Health Sciences, University of California Davis, Davis, CA 95616, USA.

Moisés Chavira-Flores (M)

Instituto de Investigaciones en Matemáticas Aplicadas y Sistemas (IIMAS), Universidad Nacional Autónoma de México (UNAM), México City 04510, Mexico.

Osval A Montesinos-López (OA)

Facultad de Telemática, Universidad de Colima, Colima 28040, Colima, Mexico.

José Crossa (J)

International Maize and Wheat Improvement Center (CIMMYT), Km 45, Carretera Mexico, Veracruz 52640, Edo. de México, Mexico.
Colegio de Postgraduados, Montecillos 56230, Edo. de México, Mexico.

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Classifications MeSH