seco-Sesquiterpenes and acorane-type sesquiterpenes with antiviral activity from the twigs and leaves of Illicium henryi Diels.

Acorane-type sesquiterpenes Antiviral activity Chemical transformation Illicium henryi Diels seco-Sesquiterpenes

Journal

Bioorganic chemistry
ISSN: 1090-2120
Titre abrégé: Bioorg Chem
Pays: United States
ID NLM: 1303703

Informations de publication

Date de publication:
02 2023
Historique:
received: 20 10 2022
revised: 04 12 2022
accepted: 11 12 2022
pubmed: 24 12 2022
medline: 21 1 2023
entrez: 23 12 2022
Statut: ppublish

Résumé

Chemical investigation of an alcohol extract from the twigs and leaves of Illicium henryi Diels resulted in the isolation of two new acorane-related seco-sesquiterpenes (1 and 3), two new acorane-related seco-norsesquiterpenes (2 and 4), one new 2-epi-cedrane sesquiterpene (5), eight new acorane-type sesquiterpenes (6-13), and a known major constituent of acorenone B (14). Their structures were established by interpreting extensive spectroscopic data, including HRESIMS, NMR (

Identifiants

pubmed: 36563414
pii: S0045-2068(22)00731-3
doi: 10.1016/j.bioorg.2022.106324
pii:
doi:

Substances chimiques

Antiviral Agents 0
Sesquiterpenes 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

106324

Informations de copyright

Copyright © 2022 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Jin-Yao Yong (JY)

State Key Laboratory of Bioactive Sub Stance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, People's Republic of China.

Mi Li (M)

State Key Laboratory of Bioactive Sub Stance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, People's Republic of China.

Wen-Rui Li (WR)

State Key Laboratory of Bioactive Sub Stance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, People's Republic of China.

Rong-Mei Gao (RM)

Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, People's Republic of China.

Guo-Zhu Su (GZ)

State Key Laboratory of Bioactive Sub Stance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, People's Republic of China.

Hai-Qiang Wang (HQ)

State Key Laboratory of Bioactive Sub Stance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, People's Republic of China.

Jia Yang (J)

State Key Laboratory of Bioactive Sub Stance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, People's Republic of China.

Li Li (L)

State Key Laboratory of Bioactive Sub Stance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, People's Republic of China.

Yu-Huan Li (YH)

Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, People's Republic of China.

Peter Scott (P)

Department of Chemistry, University of Warwick, Coventry CV4 7AL, UK.

Ru-Bing Wang (RB)

State Key Laboratory of Bioactive Sub Stance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, People's Republic of China. Electronic address: wangrubing@imm.ac.cn.

Xiao-Jing Wang (XJ)

State Key Laboratory of Bioactive Sub Stance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, People's Republic of China. Electronic address: wangxiaojing@imm.ac.cn.

Shuang-Gang Ma (SG)

State Key Laboratory of Bioactive Sub Stance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, People's Republic of China. Electronic address: mashuanggang@imm.ac.cn.

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Classifications MeSH