Constructing 3D In Vitro Models of Heterocellular Solid Tumors and Stromal Tissues Using Extrusion-Based Bioprinting.

Animals Bioprinting / methods Reproducibility of Results Printing, Three-Dimensional Neoplasms Biocompatible Materials Tumor Microenvironment
extrusion bioprinting miniaturized tumor subsystems tumor microenvironment

Journal

ACS biomaterials science & engineering
ISSN: 2373-9878
Titre abrégé: ACS Biomater Sci Eng
Pays: United States
ID NLM: 101654670

Informations de publication

Date de publication:
13 02 2023
Historique:
pubmed: 5 1 2023
medline: 15 2 2023
entrez: 4 1 2023
Statut: ppublish

Résumé

Malignant tumor tissues exhibit inter- and intratumoral heterogeneities, aberrant development, dynamic stromal composition, diverse tissue phenotypes, and cell populations growing within localized mechanical stresses in hypoxic conditions. Experimental tumor models employing engineered systems that isolate and study these complex variables using

Identifiants

DOI: 10.1021/acsbiomaterials.2c00998 PMID: 36598339
pubmed: 36598339
doi: 10.1021/acsbiomaterials.2c00998
doi:

Substances chimiques

Biocompatible Materials 0

Types de publication

Journal Article Review Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

542-561

Auteurs

Salvador Flores-Torres (S)

Department of Bioengineering, McGill University, Montreal, Quebec H3A 0G4, Canada.
ORCID: 0000-0002-2947-9786

Tao Jiang (T)

Department of Intelligent Machinery and Instrument, College of Intelligence Science and Technology, National University of Defense Technology Changsha, Hunan 410073, China.
ORCID: 0000-0002-9406-5061

Jacqueline Kort-Mascort (J)

Department of Bioengineering, McGill University, Montreal, Quebec H3A 0G4, Canada.
ORCID: 0000-0003-0650-3162

Yun Yang (Y)

Department of Intelligent Machinery and Instrument, College of Intelligence Science and Technology, National University of Defense Technology Changsha, Hunan 410073, China.

Omar Peza-Chavez (O)

Department of Bioengineering, McGill University, Montreal, Quebec H3A 0G4, Canada.
ORCID: 0000-0002-8762-8276

Sanjima Pal (S)

Department of Surgery, McGill University, Montreal, Quebec H3G 2M1, Canada.

Alisia Mainolfi (A)

Department of Bioengineering, McGill University, Montreal, Quebec H3A 0G4, Canada.

Lucas Antonio Pardo (LA)

Department of Bioengineering, McGill University, Montreal, Quebec H3A 0G4, Canada.
ORCID: 0000-0003-3750-6788

Lorenzo Ferri (L)

Department of Surgery, McGill University, Montreal, Quebec H3G 2M1, Canada.
Department of Medicine, McGill University, Montreal, Quebec H3G 2M1, Canada.

Nicholas Bertos (N)

Research Institute of the McGill University Health Centre (RI-MUHC), Montreal, Quebec H4A 3J1, Canada.
ORCID: 0000-0001-5466-6076

Veena Sangwan (V)

Department of Surgery, McGill University, Montreal, Quebec H3G 2M1, Canada.

Joseph M Kinsella (JM)

Department of Bioengineering, McGill University, Montreal, Quebec H3A 0G4, Canada.
ORCID: 0000-0002-3052-0782

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Classifications MeSH

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