Skin-Derived ABCB5

ABCB5 advanced-therapy medicinal product angiogenesis cell therapy chronic wound epidermolysis bullosa immunomodulation inflammation mesenchymal stem cells wound healing

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
21 Dec 2022
Historique:
received: 11 11 2022
revised: 16 12 2022
accepted: 17 12 2022
entrez: 8 1 2023
pubmed: 9 1 2023
medline: 11 1 2023
Statut: epublish

Résumé

The ATP-binding cassette superfamily member ABCB5 identifies a subset of skin-resident mesenchymal stem cells (MSCs) that exhibit potent immunomodulatory and wound healing-promoting capacities along with superior homing ability. The ABCB5

Identifiants

pubmed: 36613507
pii: ijms24010066
doi: 10.3390/ijms24010066
pmc: PMC9820160
pii:
doi:

Substances chimiques

ABCB5 protein, human 0
ATP Binding Cassette Transporter, Subfamily B 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NHLBI NIH HHS
ID : 1R01HL161087
Pays : United States
Organisme : NEI NIH HHS
ID : R24 EY028767
Pays : United States
Organisme : NEI NIH HHS
ID : R01 EY025794
Pays : United States
Organisme : NEI NIH HHS
ID : RO1EY025794
Pays : United States
Organisme : NIA NIH HHS
ID : P01 AG071463
Pays : United States
Organisme : NEI NIH HHS
ID : R24EY028767
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL161087
Pays : United States

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Auteurs

Elke Niebergall-Roth (E)

TICEBA GmbH, 69120 Heidelberg, Germany.

Natasha Y Frank (NY)

Department of Medicine, VA Boston Healthcare System, Boston, MA 02132, USA.
Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Harvard Stem Cell Institute, Harvard University, Cambridge, MA 02138, USA.
Transplant Research Program, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.

Christoph Ganss (C)

TICEBA GmbH, 69120 Heidelberg, Germany.
RHEACELL GmbH & Co. KG, 69120 Heidelberg, Germany.

Markus H Frank (MH)

Harvard Stem Cell Institute, Harvard University, Cambridge, MA 02138, USA.
Transplant Research Program, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
School of Medical and Health Sciences, Edith Cowan University, Perth 6027, Australia.

Mark A Kluth (MA)

TICEBA GmbH, 69120 Heidelberg, Germany.
RHEACELL GmbH & Co. KG, 69120 Heidelberg, Germany.

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Classifications MeSH