Prediction of type 2 diabetes mellitus using hematological factors based on machine learning approaches: a cohort study analysis.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
12 01 2023
12 01 2023
Historique:
received:
18
10
2022
accepted:
30
12
2022
entrez:
12
1
2023
pubmed:
13
1
2023
medline:
17
1
2023
Statut:
epublish
Résumé
Type 2 Diabetes Mellitus (T2DM) is a significant public health problem globally. The diagnosis and management of diabetes are critical to reduce the diabetes complications including cardiovascular disease and cancer. This study was designed to assess the potential association between T2DM and routinely measured hematological parameters. This study was a subsample of 9000 adults aged 35-65 years recruited as part of Mashhad stroke and heart atherosclerotic disorder (MASHAD) cohort study. Machine learning techniques including logistic regression (LR), decision tree (DT) and bootstrap forest (BF) algorithms were applied to analyze data. All data analyses were performed using SPSS version 22 and SAS JMP Pro version 13 at a significant level of 0.05. Based on the performance indices, the BF model gave high accuracy, precision, specificity, and AUC. Previous studies suggested the positive relationship of triglyceride-glucose (TyG) index with T2DM, so we considered the association of TyG index with hematological factors. We found this association was aligned with their results regarding T2DM, except MCHC. The most effective factors in the BF model were age and WBC (white blood cell). The BF model represented a better performance to predict T2DM. Our model provides valuable information to predict T2DM like age and WBC.
Identifiants
pubmed: 36635303
doi: 10.1038/s41598-022-27340-2
pii: 10.1038/s41598-022-27340-2
pmc: PMC9837189
doi:
Substances chimiques
Glucose
IY9XDZ35W2
Triglycerides
0
Blood Glucose
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
663Informations de copyright
© 2023. The Author(s).
Références
BMC Bioinformatics. 2013 Feb 23;14:64
pubmed: 23433084
Diabetes Metab. 2013 May;39(3):271-5
pubmed: 23628550
Vasc Health Risk Manag. 2013;9:237-43
pubmed: 23690689
Int J Public Health. 2015 Jul;60(5):561-72
pubmed: 25943424
Diabet Med. 2007 Apr;24(4):333-43
pubmed: 17367307
Transl Res. 2021 Feb;228:42-51
pubmed: 32827706
Diabetes. 2002 Feb;51(2):455-61
pubmed: 11812755
J Abnorm Psychol. 1989 Aug;98(3):229-35
pubmed: 2768657
J Intern Med. 2014 Aug;276(2):174-83
pubmed: 24471821
J Lab Physicians. 2012 Jan;4(1):5-9
pubmed: 22923915
Turk J Med Sci. 2014;44(1):121-5
pubmed: 25558571
Maedica (Bucur). 2021 Sep;16(3):375-381
pubmed: 34925590
Biofactors. 2021 Nov;47(6):1032-1041
pubmed: 34609029
Pan Afr Med J. 2014 May 12;18:42
pubmed: 25368731
Diabetes Metab Syndr Obes. 2020 Oct 23;13:3937-3946
pubmed: 33122930
J Clin Lab Anal. 2023 Jan;37(1):e24798
pubmed: 36510349
Indian J Clin Biochem. 2008 Jul;23(3):223-6
pubmed: 23105758
IEEE J Biomed Health Inform. 2019 Sep;23(5):2182-2188
pubmed: 30235154
Ren Fail. 2018 Nov;40(1):590-596
pubmed: 30371119
Ren Fail. 2015 May;37(4):659-63
pubmed: 25682974
Int J Clin Exp Med. 2015 Jul 15;8(7):11420-7
pubmed: 26379958
J Med Biochem. 2019 Mar 03;38(2):164-171
pubmed: 30867644
Front Public Health. 2021 Nov 01;9:611652
pubmed: 34790639
J Clin Endocrinol Metab. 2019 May 1;104(5):1520-1574
pubmed: 30903688
Heliyon. 2020 Dec;6(12):e05704
pubmed: 33324768
Diabetes Res Clin Pract. 2019 Nov;157:107843
pubmed: 31518657
Int J Clin Exp Med. 2014 Aug 15;7(8):2292-7
pubmed: 25232423
Crit Rev Clin Lab Sci. 2021 Jun;58(4):275-296
pubmed: 33739235
Prim Care Diabetes. 2020 Apr;14(2):161-167
pubmed: 31466834
Diabetes Metab Res Rev. 2015 May;31(4):402-10
pubmed: 25421610
Diabetes Metab Syndr. 2018 May;12(3):309-312
pubmed: 29287841
Biomed J. 2021 Jun;44(3):304-316
pubmed: 34127421
N Am J Med Sci. 2011 Jul;3(7):344-7
pubmed: 22540111
Pak J Med Sci. 2013 Jan;29(1):152-6
pubmed: 24353529
BMC Endocr Disord. 2018 May 30;18(1):33
pubmed: 29843706
BMJ. 2018 Sep 4;362:k1497
pubmed: 30181166
Am J Med. 1981 Feb;70(2):339-52
pubmed: 7008587
Clin Pharmacol Ther. 2007 Sep;82(3):275-81
pubmed: 17361126
Diabetes Metab J. 2013 Dec;37(6):423-8
pubmed: 24404513
Diabetes Metab Syndr. 2019 Jan - Feb;13(1):560-563
pubmed: 30641766
Diabetes Metab. 2016 Dec;42(6):448-452
pubmed: 27209441
Prim Care Diabetes. 2015 Jun;9(3):226-30
pubmed: 25249479
PLoS One. 2021 Jun 14;16(6):e0253286
pubmed: 34125859
J Diabetes Complications. 2004 May-Jun;18(3):173-6
pubmed: 15145330
Diabetes Res Clin Pract. 2018 Jul;141:140-147
pubmed: 29730387
J Clin Lab Anal. 2021 Jun;35(6):e23770
pubmed: 34028874
Prev Med. 2016 May;86:99-105
pubmed: 26854766