Physiologically-obtainable polyphenol exposures modulate reactive oxygen and nitrogen species signaling in the C2C12 model of skeletal muscle ageing.


Journal

European journal of pharmacology
ISSN: 1879-0712
Titre abrégé: Eur J Pharmacol
Pays: Netherlands
ID NLM: 1254354

Informations de publication

Date de publication:
15 Feb 2023
Historique:
received: 10 09 2022
revised: 10 01 2023
accepted: 13 01 2023
pubmed: 17 1 2023
medline: 1 2 2023
entrez: 16 1 2023
Statut: ppublish

Résumé

Age-related frailty is a significant health and social care burden, with limited treatment options. There is a lack of suitable cell culture model for screening large numbers of test compounds to identify those which promote healthy skeletal muscle function. This paper describes the characterization of reactive oxygen and nitrogen species (RONS) signalling changes in young and aged myoblasts and myotubes using C

Identifiants

pubmed: 36646202
pii: S0014-2999(23)00022-5
doi: 10.1016/j.ejphar.2023.175511
pii:
doi:

Substances chimiques

Kaempferols 0
Nitrogen N762921K75
Oxygen S88TT14065
Polyphenols 0
Reactive Nitrogen Species 0
Reactive Oxygen Species 0
Resveratrol Q369O8926L

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

175511

Informations de copyright

Copyright © 2023 The Author(s). Published by Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest None.

Auteurs

Nathan Hayes (N)

Department of Biological and Marine Sciences, University of Hull, Hull, HU6 7RX, UK.

Mark Fogarty (M)

Leeds Trinity University, Leeds, LS18 5HD, UK.

Laura Sadofsky (L)

Centre for Atherothrombotic and Metabolic Research, Hull York Medical School, Hull, HU6 7RX, UK.

Huw Simon Jones (HS)

Institute of Cancer Therapeutics, University of Bradford, Bradford, BD7 1DP, UK. Electronic address: h.s.jones@bradford.ac.uk.

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Classifications MeSH