Crystal Structure and Biochemical Analysis of a Cytochrome P450 Steroid Hydroxylase (
Crystal structure
X-ray crystallography
cytochrome P450
steroid hydroxylase
Journal
Journal of microbiology and biotechnology
ISSN: 1738-8872
Titre abrégé: J Microbiol Biotechnol
Pays: Korea (South)
ID NLM: 9431852
Informations de publication
Date de publication:
28 Mar 2023
28 Mar 2023
Historique:
received:
16
11
2022
revised:
05
12
2022
accepted:
06
12
2022
medline:
29
3
2023
pubmed:
20
1
2023
entrez:
19
1
2023
Statut:
ppublish
Résumé
Cytochrome P450 (CYP) is a heme-containing enzyme that catalyzes hydroxylation reactions with various substrate molecules. Steroid hydroxylases are particularly useful for effectively introducing hydroxyl groups into a wide range of steroids in the pharmaceutical industry. This study reports a newly identified CYP steroid hydroxylase (
Identifiants
pubmed: 36655276
pii: jmb.2211.11031
doi: 10.4014/jmb.2211.11031
pmc: PMC10084758
doi:
Substances chimiques
Cytochrome P-450 Enzyme System
9035-51-2
Steroid Hydroxylases
EC 1.14.-
Steroids
0
Progesterone
4G7DS2Q64Y
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
387-397Références
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