Insomnia severity predicts depression, anxiety, and posttraumatic stress disorder in veterans with spinal cord injury or disease: a cross-sectional observational study.
anxiety
depression
insomnia
posttraumatic stress disorder
spinal cord diseases
spinal cord injury
Journal
Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine
ISSN: 1550-9397
Titre abrégé: J Clin Sleep Med
Pays: United States
ID NLM: 101231977
Informations de publication
Date de publication:
01 04 2023
01 04 2023
Historique:
pmc-release:
01
04
2024
medline:
5
4
2023
pubmed:
21
1
2023
entrez:
20
1
2023
Statut:
ppublish
Résumé
To assess the association of insomnia symptoms and psychiatric symptoms in patients with spinal cord injury or disease (SCI/D). In this cross-sectional observational study, veterans with SCI/D (n = 72; mean = 59.85 ± 10.4 years; 92% male) completed baseline measures, including the Insomnia Severity Index (ISI) during the baseline phase of a clinical trial on treatment of sleep disorders in veterans with SCI/D. Depression severity was measured by the Patient Health Questionnaire (PHQ-9; sleep items excluded), anxiety severity was measured by the Generalized Anxiety Disorder screener (GAD-7), and probable posttraumatic stress disorder (PTSD) was measured by the Primary Care PTSD screener. Blocked regression was used to evaluate the impact of insomnia symptoms (ISI) on mental health measures after accounting for demographics and level of spinal cord injury/disease. On average, participants scored in the mild range for depression (PHQ-9 = 7.4 ± 5.9) and anxiety severity (GAD-7 = 6.1 ± 6.1). In total, 36.1% (n = 26) screened positive for probable PTSD. ISI explained 19% of the variance in PHQ-9 and 20% of the variance in GAD-7 ( In veterans with SCI/D, insomnia severity was linked to depression and anxiety symptom severity and risk of PTSD. Study results warrant further research to evaluate the impact of insomnia treatment on depression, anxiety, and PTSD in patients with SCI/D. Registry: ClinicalTrials.gov; Name: Treatment of Sleep-disordered Breathing in Patients With SCI; URL: https://clinicaltrials.gov/ct2/show/NCT02830074; Identifier: NCT02830074. Kelly MR, Zeineddine S, Mitchell MN, et al. Insomnia severity predicts depression, anxiety, and posttraumatic stress disorder in veterans with spinal cord injury or disease: a cross-sectional observational study.
Identifiants
pubmed: 36661092
pii: jcsm.10410
doi: 10.5664/jcsm.10410
pmc: PMC10071376
doi:
Banques de données
ClinicalTrials.gov
['NCT02830074']
Types de publication
Observational Study
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
695-701Subventions
Organisme : BLRD VA
ID : I01 BX002780
Pays : United States
Organisme : NHLBI NIH HHS
ID : K24 HL143055
Pays : United States
Informations de copyright
© 2023 American Academy of Sleep Medicine.
Références
Arch Phys Med Rehabil. 2015 Jan;96(1):133-40
pubmed: 25220943
J Clin Sleep Med. 2017 May 15;13(5):665-666
pubmed: 28416048
Sci Rep. 2021 May 13;11(1):10173
pubmed: 33986414
Sleep. 2014 Feb 01;37(2):327-41
pubmed: 24497661
Sleep. 2013 Jul 01;36(7):1009-1018
pubmed: 23814337
Am J Public Health. 2015 Dec;105(12):2564-9
pubmed: 26474009
J Affect Disord. 2017 Oct 15;221:25-30
pubmed: 28628764
J Clin Sleep Med. 2014 Sep 15;10(9):1025-31
pubmed: 25142763
J Affect Disord. 2007 Nov;103(1-3):77-82
pubmed: 17321595
J Gen Intern Med. 2001 Sep;16(9):606-13
pubmed: 11556941
Sleep. 2009 Aug;32(8):1027-37
pubmed: 19725254
Disabil Health J. 2014 Oct;7(4):466-71
pubmed: 25224987
J Rehabil Res Dev. 2012;49(7):1115-26
pubmed: 23341283
Arch Intern Med. 2006 May 22;166(10):1092-7
pubmed: 16717171
Aust N Z J Psychiatry. 2008 Apr;42(4):309-14
pubmed: 18330773
Depress Anxiety. 2018 Nov;35(11):1048-1055
pubmed: 30099820
Chest. 2019 Feb;155(2):438-445
pubmed: 30321507
Ann N Y Acad Sci. 2008;1129:287-304
pubmed: 18591489
Gen Hosp Psychiatry. 1995 Nov;17(6):440-3
pubmed: 8714804
Arch Gen Psychiatry. 2005 Jun;62(6):617-27
pubmed: 15939839
Curr Sleep Med Rep. 2017 Dec;3(4):272-278
pubmed: 29177130
J Gen Intern Med. 2016 Oct;31(10):1206-11
pubmed: 27170304
Acta Neurol Scand. 2004 Jul;110(1):6-13
pubmed: 15180801
Sleep Med Rev. 2010 Feb;14(1):69-82
pubmed: 19962922
Sleep. 2011 May 01;34(5):601-8
pubmed: 21532953
Spinal Cord. 2009 Feb;47(2):108-14
pubmed: 18779835
Ann Intern Med. 2020 Mar 3;172(5):325-336
pubmed: 32066145
JAMA Psychiatry. 2015 Mar;72(3):247-58
pubmed: 25607727
Gen Hosp Psychiatry. 2010 Jul-Aug;32(4):345-59
pubmed: 20633738
Ann Intern Med. 2016 Jul 19;165(2):125-33
pubmed: 27136449
J Clin Sleep Med. 2019 May 15;15(5):719-724
pubmed: 31053202
Spinal Cord. 2018 Aug;56(8):750-761
pubmed: 29581519
J Clin Sleep Med. 2016 May 15;12(5):695-701
pubmed: 26857058
J Clin Sleep Med. 2014 Jan 15;10(1):65-72
pubmed: 24426822
Sleep. 2008 Apr;31(4):489-95
pubmed: 18457236
Sleep Med. 2001 Jul;2(4):297-307
pubmed: 11438246
Paraplegia. 1995 Feb;33(2):62-8
pubmed: 7753569
Mult Scler Relat Disord. 2015 Sep;4(5):477-483
pubmed: 26346798
J Trauma Stress. 2014 Oct;27(5):542-9
pubmed: 25267288
J Clin Sleep Med. 2015 Sep 15;11(9):995-1005
pubmed: 26094928
Arch Phys Med Rehabil. 2011 Mar;92(3):411-8
pubmed: 21353823
Sleep Med. 2009 Jan;10(1):26-34
pubmed: 18207453
J Behav Med. 2011 Apr;34(2):92-101
pubmed: 20809354
Sleep Med Rev. 2013 Dec;17(6):399-409
pubmed: 23618534
Arch Phys Med Rehabil. 2017 Aug;98(8):1508-1517.e2
pubmed: 28400181
Psychol Aging. 1986 Sep;1(3):233-8
pubmed: 3267403