Fatal Progression of Mutated TP53-Associated Clonal Hematopoiesis following Anti-CD19 CAR-T Cell Therapy.
CAR-T cell therapy
clonal evolution
clonal hematopoiesis
therapy-related neoplasia
Journal
Current oncology (Toronto, Ont.)
ISSN: 1718-7729
Titre abrégé: Curr Oncol
Pays: Switzerland
ID NLM: 9502503
Informations de publication
Date de publication:
13 01 2023
13 01 2023
Historique:
received:
06
12
2022
revised:
06
01
2023
accepted:
11
01
2023
entrez:
20
1
2023
pubmed:
21
1
2023
medline:
25
1
2023
Statut:
epublish
Résumé
We present the case of a 64-year-old man diagnosed with large B-cell lymphoma who relapsed twice after standard-of-care therapy. Due to persisting cytopenia, Next generation sequencing analysis was performed, revealing a small
Identifiants
pubmed: 36661736
pii: curroncol30010087
doi: 10.3390/curroncol30010087
pmc: PMC9858310
doi:
Substances chimiques
Antigens, CD19
0
Receptors, Chimeric Antigen
0
TP53 protein, human
0
Tumor Suppressor Protein p53
0
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
1146-1150Références
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