Cohort Profile: CArdiovascular Risk in patients with DIAbetes in NAvarra (CARDIANA cohort).
Cardiac Epidemiology
General diabetes
Health informatics
Risk management
Journal
BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874
Informations de publication
Date de publication:
20 01 2023
20 01 2023
Historique:
entrez:
20
1
2023
pubmed:
21
1
2023
medline:
25
1
2023
Statut:
epublish
Résumé
The CArdiovascular Risk in patients with DIAbetes in Navarra (CARDIANA cohort) cohort was established to assess the effects of sociodemographic and clinical variables on the risk of cardiovascular events in patients with type 1 (T1D) or type 2 (T2D) diabetes, with a special focus on socioeconomic factors, and to validate and develop cardiovascular risk models for these patients. The CARDIANA cohort included all patients with T1D and T2D diabetes registered in the Public Health Service of Navarra with prevalent disease on 1 January 2012. It consisted of 1067 patients with T1D (ages 2-88 years) and 33842 patients with T2D (ages 20-105 years), whose data were retrospectively extracted from the Health and Administrative System Databases. The follow-up period for wave 1 was from 1 January 2012 to 31 December 2016. During these 5 years, 9 patients (0.8%; 95% CI (0.4% to 1.6%)) in the T1D cohort developed a cardiovascular disease event, whereas for the T2D cohort, 2602 (7.7%; 95% CI (7.4% to 8.0%)) had an event. For the T2D cohort, physical activity was associated with a reduced risk of cardiovascular events, with adjusted estimated ORs equal to 0.84 (95% CI 0.66 to 1.07) for the partially active group and 0.71 (95% CI 0.56 to 0.91) for the active group, compared with patients in the non-active group. The CARDIANA cohort is currently being used to assess the effect of sociodemographic risk factors on CV risk at 5 years and to externally validate cardiovascular predictive models. A second wave is being conducted in late 2022 and early 2023, to extend the follow-up other 5 years, from 1 January 2016 to 31 December 2021. Periodic data extractions are planned every 5 years.
Identifiants
pubmed: 36669840
pii: bmjopen-2022-066052
doi: 10.1136/bmjopen-2022-066052
pmc: PMC9872484
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e066052Informations de copyright
© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
Références
Aten Primaria. 2017 Apr;49(4):240-247
pubmed: 27592535
Gac Sanit. 2017 Jan - Feb;31(1):23-29
pubmed: 27856017
Lancet. 2020 Nov 14;396(10262):1535
pubmed: 33189162
Diabetes Res Clin Pract. 2022 Feb;184:109089
pubmed: 34648890
Clin Epidemiol. 2018 Jul 27;10:863-874
pubmed: 30100760
Int J Environ Res Public Health. 2021 Nov 24;18(23):
pubmed: 34886096
Physiol Rev. 2013 Jan;93(1):137-88
pubmed: 23303908
Curr Cardiovasc Risk Rep. 2015;9(7):36
pubmed: 26029318
Eur Heart J. 2021 Jul 1;42(25):2439-2454
pubmed: 34120177
BMC Med Inform Decis Mak. 2017 Apr 8;17(1):34
pubmed: 28390396
BMC Public Health. 2018 Mar 27;18(1):408
pubmed: 29587788
Diabet Med. 2017 May;34(5):662-666
pubmed: 27353285
J Chronic Dis. 1987;40(5):373-83
pubmed: 3558716
PLoS Med. 2012;9(10):e1001321
pubmed: 23055834
Aten Primaria. 2016 Dec;48(10):674-682
pubmed: 27495004
Diabetologia. 2012 Jan;55(1):88-93
pubmed: 21987347