Military service and risk of subsequent drug use disorders among Swedish men.

Drug use disorder Instrumental variable Military service Registry data

Journal

Social psychiatry and psychiatric epidemiology
ISSN: 1433-9285
Titre abrégé: Soc Psychiatry Psychiatr Epidemiol
Pays: Germany
ID NLM: 8804358

Informations de publication

Date de publication:
Jul 2023
Historique:
received: 03 03 2022
accepted: 12 01 2023
medline: 14 6 2023
pubmed: 22 1 2023
entrez: 21 1 2023
Statut: ppublish

Résumé

Environmental factors contribute substantially to risk for drug use disorders (DUD). The current study applies multiple methods to empirically test whether military service is associated with subsequent DUD, as previous findings are inconsistent. Longitudinal Swedish national registry data on a cohort of male conscripts born 1972-1987 (maximum N = 485,900) were used to test the association between military service and subsequent registration for DUD. Cox proportional hazard models were used in preliminary analyses, followed by three methods that enable causal inference: propensity score models, co-relative models, and instrumental variable analysis. Across all methods, military service was causally associated with lower risk of DUD. Hazard ratios ranged from HR = 0.43 (95% confidence intervals [CI] 0.37; 0.50) in the instrumental variable analysis to 0.77 (0.75; 0.79) in the multivariate propensity score matching analysis. This effect diminished across time. In the model including a propensity score, HRs remained below 1 across the observation period, while confidence intervals included 1 after ~ 11 years in the co-relative analysis and after ~ 21 years in the instrumental variable analysis. In this cohort of Swedish men, complementary methods indicate that military service conferred substantial but time-limited protection against subsequent DUD. The observed effect could be due to reduced opportunity for substance use during service, social cohesion experienced during and after service, and/or socioeconomic advantages among veterans. Additional research is necessary to clarify these protective mechanisms and determine how other environmental contexts can provide similar benefits.

Identifiants

pubmed: 36680575
doi: 10.1007/s00127-023-02426-y
pii: 10.1007/s00127-023-02426-y
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1039-1048

Subventions

Organisme : NIDA NIH HHS
ID : R01 DA030005
Pays : United States
Organisme : NIAAA NIH HHS
ID : AA027522
Pays : United States
Organisme : NIDA NIH HHS
ID : DA030005
Pays : United States
Organisme : NIAAA NIH HHS
ID : AA023534
Pays : United States

Informations de copyright

© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany.

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Auteurs

Alexis C Edwards (AC)

Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Box 980126, RichmondRichmond, VA, 23298-0126, USA. alexis.edwards@vcuhealth.org.

Henrik Ohlsson (H)

Center for Primary Health Care Research, Lund University, Malmö, Sweden.

Peter B Barr (PB)

Department of Psychiatry and Behavioral Sciences, State University of New York-Downstate, Brooklyn, NY, USA.

Jan Sundquist (J)

Center for Primary Health Care Research, Lund University, Malmö, Sweden.
Department of Family Medicine and Community Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Kenneth S Kendler (KS)

Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Box 980126, RichmondRichmond, VA, 23298-0126, USA.

Kristina Sundquist (K)

Center for Primary Health Care Research, Lund University, Malmö, Sweden.
Department of Family Medicine and Community Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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